SCHEMBL3404341

SCHEMBL3404341

CCC(=O)c1ccc(C(C)C)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP5 P45974 1/20 0.63
SMN1; SMN2 Q16637 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
MAPT P10636 1/20 0.53
POLB P06746 1/20 0.53
CYP2C9 P11712 1/20 0.50
PPARG P37231 4/20 0.49
PPARA Q07869 4/20 0.49
HTT P42858 1/20 0.47
RAB9A P51151 3/20 0.46
ALDH1A1 P00352 2/20 0.46
KDM4E B2RXH2 1/20 0.46
NPC1 O15118 1/20 0.46
HPGD P15428 1/20 0.46
MPI P34949 1/20 0.46
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
LMNA P02545 1/20 0.46
RXRA P19793 1/20 0.45
RXRB P28702 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL28686261 0.98 USP5 (0.61) USP5SMN1; SMN2L3MBTL1MAPTPOLB
Hydrochloric Acid SCHEMBL28093688 0.98 USP5 (0.61) USP5SMN1; SMN2L3MBTL1MAPTPOLB
Butane SCHEMBL10985150 0.96 USP5 (0.59) USP5SMN1; SMN2L3MBTL1MAPTPOLB
SCHEMBL2627842 0.94 L3MBTL1 (0.63) USP5SMN1; SMN2L3MBTL1MAPTPOLB
SCHEMBL30089581 0.84 USP5 (0.85) USP5SMN1; SMN2L3MBTL1POLBCYP2C9
SCHEMBL269939 0.84 USP5 (0.66) USP5SMN1; SMN2L3MBTL1MAPTPOLB
SCHEMBL17577071 0.84 USP5 (0.56) USP5SMN1; SMN2L3MBTL1POLBCYP2C9
SCHEMBL11464173 0.83 USP5 (0.70) USP5SMN1; SMN2L3MBTL1POLBCYP2C9
SCHEMBL8051337 0.83 SMN1; SMN2 (0.70) SMN1; SMN2L3MBTL1MAPTHTTRAB9A
SCHEMBL17049803 0.83 SMN1; SMN2 (0.50) USP5SMN1; SMN2L3MBTL1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-205838883-U A kind of process units of cyclamen aldehyde precursor p-isopropyl β chlorine α methylbenzene acrylic aldehyde 安徽华业香料股份有限公司 2016-12-28 CN claimed
CN-205838882-U A kind of industrial installation of high-load cyclamen aldehyde 安徽华业香料股份有限公司 2016-12-28 CN claimed
CN-106220486-A A kind of synthetic method of high-load cyclamen aldehyde spice 安徽华业香料股份有限公司 2016-12-14 CN claimed
CN-106187719-A The synthetic method of cyclamen aldehyde precursor p-isopropyl β chlorine α methylbenzene acrylic aldehyde 安徽华业香料股份有限公司 2016-12-07 CN claimed
CN-106187728-A A kind of industrial process of high-load cyclamen aldehyde 安徽华业香料股份有限公司 2016-12-07 CN claimed
CN-106187720-A The industrial process of cyclamen aldehyde precursor p-isopropyl β chlorine α methylbenzene acrylic aldehyde 安徽华业香料股份有限公司 2016-12-07 CN claimed
CN-104177298-A 4, 4-disubstituted-4, 5-dihydro-1H-imidazole-5-one and derivatives thereof as well as synthesis method thereof UNIV XIANGTAN 2014-12-03 CN claimed
CN-114007660-B Refreshing composition and method for atomizing refreshing composition by using heat-activated microfluidic cartridge 宝洁公司 2024-07-05 CN disclosed
US-11998664-B2 Ureteral stent and manufacture method therefor JIANGSU BIOSURF BIOTECH CO., LTD (CN) 2024-06-04 US disclosed
CN-114096283-B Method of atomizing a fluid composition 宝洁公司 2024-04-16 CN disclosed
US-11938208-B2 Antimicrobial mixture SYMRISE AG (DE) 2024-03-26 US disclosed
US-11873295-B2 Allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) for the treatment of disease PETRA PHARMA CORPORATION (US) 2024-01-16 US disclosed
US-20230348369-A1 NAMPT MODULATORS CYTOKINETICS, INC. 2023-11-02 US disclosed
EP-0052775-A2 Process for the production of aldehydes and intermediate products L. GIVAUDAN & CIE Société Anonyme (CH) 1982-06-02 EP disclosed
US-4237306-A ELECTROPHILIC REACTIONS WITH ALKYL ARYL KETONES TO PRODUCE METHYL ARYL ALKANOATES EMERY INDUSTRIES, INC. (US) 1980-12-02 US disclosed
US-4182730-A Process for the preparation of substituted dihydrocinnamaldehydes via novel β-chlorocinnamaldehydes GIVAUDAN CORPORATION (US) 1980-01-08 US disclosed
US-4181803-A 4'-SUBSTITUTED-2-METHYL-3-PIPERIDINO-PROPIOPHENONES; ANTISPASMODIC AGENTS, MUSCLE RELAXANTS EISAI CO., LTD. (JP) 1980-01-01 US disclosed
US-4172955-A REARRANGMENT OF A CINNAMALDEHYDE TO A PHENYLMALONDIALDEHYDE TETRAMETHYL DISACETAL EMERY INDUSTRIES, INC. (US) 1979-10-30 US disclosed
US-4067823-A Thallium(III) reagents supported on montmorillonite clay minerals and oxythallation processes for utilizing same EMERY INDUSTRIES, INC. (US) 1978-01-10 US disclosed
US-3995047-A Propiophenone derivatives in the treatment of pathological muscular conditions EISAI CO., LTD. (JA) 1976-11-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11873295-B2 Allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) for the treatment of disease PIK3CA, PIK3R4, PIK3R5 USP5 4266/4885SMN1; SMN2 1813/4885L3MBTL1 3117/4885
US-20230348369-A1 NAMPT MODULATORS NAMPT, NNT, NAPRT USP5 4857/4885SMN1; SMN2 610/4885L3MBTL1 3643/4885
US-11938208-B2 Antimicrobial mixture GNPAT, GMDS, DDOST USP5 3068/4885SMN1; SMN2 4640/4885L3MBTL1 3747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.