Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 19/20 | 0.75 |
| ▸ | ESR1 | P03372 | 17/20 | 0.75 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1378406 | 0.86 | ESR2 (1.00) | ESR2ESR1MAPTSNCA | |
| SCHEMBL23387567 | 0.83 | NPC1 (0.59) | ESR2ESR1MAPT | |
| SCHEMBL3401726 | 0.83 | ESR2 (0.75) | ESR2ESR1MAPTSNCA | |
| SCHEMBL1379385 | 0.83 | ESR2 (1.00) | ESR2ESR1MAPTSNCA | |
| SCHEMBL2582987 | 0.81 | ESR2 (0.76) | ESR2ESR1MAPT | |
| SCHEMBL2587833 | 0.81 | HDAC6 (0.60) | ESR2ESR1MAPT | |
| SCHEMBL4057301 | 0.78 | HDAC6 (0.47) | ESR2ESR1MAPT | |
| SCHEMBL24038197 | 0.78 | HDAC6 (0.57) | ESR2ESR1MAPT | |
| SCHEMBL1378590 | 0.78 | ESR2 (1.00) | ESR2ESR1MAPTSNCA | |
| SCHEMBL30791976 | 0.77 | GPR119 (0.56) | ESR2ESR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250180-A1 | PHOSPHATE DERIVATIVES OF SUBSTITUTED BENZOXAZOLES | Wyeth LLC (US) | 2010-11-17 | — | — | EP | claimed |
| WO-2009100335-A1 | PHOSPHATE DERIVATIVES OF SUBSTITUTED BENZOXAZOLES | WYETH (US) | 2009-08-13 | — | — | WO | claimed |