Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | EDNRB | P24530 | 6/20 | 0.40 |
| ▸ | EDNRA | P25101 | 6/20 | 0.40 |
| ▸ | PPIA | P62937 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529411 | 0.95 | HDAC3 (0.46) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL9449948 | 0.80 | HDAC3 (0.44) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL7052203 | 0.77 | HDAC3 (0.44) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL3720120 | 0.77 | ALDH1A1 (0.46) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL40500 | 0.76 | HDAC3 (0.59) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL30001332 | 0.76 | HDAC3 (0.59) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| Benzene SCHEMBL28538497 | 0.76 | HDAC3 (0.59) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL7052205 | 0.74 | HDAC3 (0.57) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL9449419 | 0.73 | FABP5 (0.41) | HDAC3HDAC4HDAC7HDAC8HDAC6 | |
| SCHEMBL6714576 | 0.72 | HDAC3 (0.35) | HDAC3HDAC4HDAC7HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252352-A1 | INHALER | Vectura Delivery Devices Limited (GB) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009092768-A1 | INHALER | VECTURA DELIVERY DEVICES LIMITED (GB) | 2009-07-30 | — | — | WO | disclosed |