Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1219646 | 0.85 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1219647 | 0.85 | MEN1 (0.53) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL7796626 | 0.84 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL25477166 | 0.83 | SMN1; SMN2 (0.55) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL2747548 | 0.82 | MEN1 (0.50) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL2748603 | 0.80 | NAALAD2 (0.56) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL1221478 | 0.78 | ITGA4 (0.60) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL2747164 | 0.78 | KDM4A (0.57) | MAPT | |
| SCHEMBL1221477 | 0.78 | ITGA4 (0.60) | MEN1KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL2318778 | 0.78 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250164-A2 | ANGIOTENSIN II RECEPTOR BLOCKER DERIVATIVES | Nicox S.A. (FR) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009106471-A2 | NEW ANGIOTENSIN II RECEPTOR BLOCKER DERIVATIVES | NICOX S.A. (FR) | 2009-09-03 | — | — | WO | disclosed |