Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.61 |
| ▸ | PPARG | P37231 | 5/20 | 0.61 |
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29328712 | 0.89 | PPARA (0.64) | PPARAPPARGCNR1CNR2 | |
| SCHEMBL29328702 | 0.87 | PPARA (0.63) | PPARAPPARGCNR1CNR2 | |
| SCHEMBL28392302 | 0.87 | PPARA (0.63) | PPARAPPARGCNR1CNR2 | |
| SCHEMBL29328706 | 0.87 | PPARA (0.63) | PPARAPPARGCNR1CNR2 | |
| SCHEMBL29328704 | 0.87 | PPARA (0.63) | PPARAPPARGCNR1CNR2 | |
| SCHEMBL28337010 | 0.87 | PPARA (0.62) | PPARAPPARGACHECNR1CNR2 | |
| Bromide SCHEMBL28328576 | 0.86 | PPARA (0.61) | PPARAPPARGCNR1CNR2 | |
| SCHEMBL646706 | 0.86 | PPARA (0.64) | PPARAPPARGACHECNR1CNR2 | |
| SCHEMBL29914202 | 0.85 | PPARA (0.68) | PPARAPPARGCNR1CNR2 | |
| SCHEMBL29943880 | 0.85 | PPARA (0.68) | PPARAPPARGCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10675278-B2 | Crush resistant delayed-release dosage forms | Grünenthal GmbH (DE) | 2020-06-09 | — | — | US | disclosed |
| US-20180369235-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2018-12-27 | — | — | US | disclosed |
| US-20170312271-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-9750701-B2 | Pharmaceutical dosage form | Grünenthal GmbH (DE) | 2017-09-05 | — | — | US | disclosed |
| US-20160199305-A1 | PHARMACEUTICAL DOSAGE FORM | Grünenthal GmbH (DE) | 2016-07-14 | — | — | US | disclosed |
| US-20160184297-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2016-06-30 | — | — | US | disclosed |
| US-20160120810-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | Grünenthal GmbH (DE) | 2016-05-05 | — | — | US | disclosed |
| US-20150374630-A1 | Crush resistant delayed-release dosage forms | GRUENENTHAL GMBH (DE) | 2015-12-31 | — | — | US | disclosed |
| US-20150290138-A1 | Crush resistant delayed-release dosage forms | Grünenthal GmbH (DE) | 2015-10-15 | — | — | US | disclosed |
| US-20140322311-A1 | CRUSH RESISTAN DELAYED-RELEASE DOSAGE FORM | Grünenthal GmbH (DE) | 2014-10-30 | — | — | US | disclosed |
| US-20140112984-A1 | Crush resistant delayed-release dosage forms | GRUENENTHAL GMBH (DE) | 2014-04-24 | — | — | US | disclosed |
| US-20140079780-A1 | Crush resistant delayed-release dosage forms | GRUENENTHAL GMBH (DE) | 2014-03-20 | — | — | US | disclosed |
| US-20130251759-A1 | PHARMACEUTICAL DOSAGE FORM | GRUENENTHAL GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| US-8383152-B2 | Pharmaceutical dosage form | GRUENENTHAL GMBH (DE) | 2013-02-26 | — | — | US | disclosed |
| EP-2249811-A1 | PHARMACEUTICAL DOSAGE FORM | Grünenthal GmbH (DE) | 2010-11-17 | — | — | EP | disclosed |
| US-20100151028-A1 | CRUSH RESISTANT DELAYED-RELEASE DOSAGE FORMS | GRUNENTHAL GMBH (DE) | 2010-06-17 | — | — | US | disclosed |
| US-20090202634-A1 | PHARMACEUTICAL DOSAGE FORM | GRUNENTHAL GMBH (DE) | 2009-08-13 | — | — | US | disclosed |
| WO-2009092601-A1 | PHARMACEUTICAL DOSAGE FORM | Grünenthal GmbH (DE) | 2009-07-30 | — | — | WO | disclosed |
| US-20080311187-A1 | CRUSH RESISTAN DELAYED-RELEASE DOSAGE FORM | GRUNENTHAL GMBH (DE) | 2008-12-18 | — | — | US | disclosed |
| US-20060193914-A1 | Crush resistant delayed-release dosage forms | ENDO PHARMACEUTICALS, INC. | 2006-08-31 | — | — | US | disclosed |