Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 8/20 | 0.62 |
| ▸ | PPARG | P37231 | 5/20 | 0.62 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1789805 | 0.95 | PPARA (0.56) | PPARAPPARGACHEMTNR1AMTNR1B | |
| SCHEMBL31539531 | 0.90 | CYP4F2 (0.54) | PPARAPPARGACHEMTNR1AMTNR1B | |
| SCHEMBL29328712 | 0.90 | PPARA (0.64) | PPARAPPARGCNR1CNR2 | |
| SCHEMBL28593564 | 0.89 | ACHE (0.58) | PPARAPPARGACHEMTNR1AMTNR1B | |
| SCHEMBL11206161 | 0.88 | ACHE (0.51) | PPARAPPARGACHEMTNR1AMTNR1B | |
| SCHEMBL29328702 | 0.88 | PPARA (0.63) | PPARAPPARGCNR1CNR2 | |
| SCHEMBL29328704 | 0.88 | PPARA (0.63) | PPARAPPARGCNR1CNR2 | |
| SCHEMBL29328706 | 0.88 | PPARA (0.63) | PPARAPPARGCNR1CNR2 | |
| SCHEMBL28392302 | 0.88 | PPARA (0.63) | PPARAPPARGCNR1CNR2 | |
| SCHEMBL26483161 | 0.88 | PPARA (0.54) | PPARAPPARGACHECNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105143170-B | For treating the aromatic compounds of pulmonary fibrosis, liver fibrosis, fibrosis of skin and cardiac fibrosis being substituted | 普罗米蒂克医药SMT有限公司 | 2019-11-08 | — | — | CN | disclosed |