Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 12/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3410556 | 0.98 | CYP1A2 (0.50) | CYP1A2GAAPDE4AALDH1A1POLB | |
| SCHEMBL185989 | 0.80 | GAA (0.49) | CYP1A2GAAPDE4AALDH1A1POLB | |
| SCHEMBL2534556 | 0.75 | CYP1A2 (0.70) | CYP1A2GAAPDE4AALDH1A1POLB | |
| SCHEMBL12456440 | 0.75 | CYP1A2 (0.46) | CYP1A2GAAPDE4AALDH1A1POLB | |
| SCHEMBL12456043 | 0.75 | CYP1A2 (0.46) | CYP1A2GAAPDE4AALDH1A1POLB | |
| SCHEMBL1715359 | 0.75 | CYP1A2 (0.46) | CYP1A2GAAPDE4AALDH1A1POLB | |
| SCHEMBL2538688 | 0.73 | CYP1A2 (0.72) | CYP1A2GAAPDE4AALDH1A1POLB | |
| SCHEMBL193707 | 0.72 | CYP1A2 (0.71) | CYP1A2GAAPDE4AALDH1A1POLB | |
| SCHEMBL12456474 | 0.72 | CYP1A2 (0.47) | CYP1A2GAAPDE4AALDH1A1POLB | |
| SCHEMBL12456471 | 0.72 | CYP1A2 (0.44) | CYP1A2GAAPDE4AALDH1A1JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197851-A1 | DERIVATIVES OF N-PHENYLACETAMIDE AS INHIBITORS OF THE ENZYME SOAT1 FOR PHARMACEUTICAL AND COSMETIC USE | Galderma Research & Development (FR) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009030750-A1 | DERIVATIVES OF N-PHENYLACETAMIDE AS INHIBITORS OF THE ENZYME SOAT1 FOR PHARMACEUTICAL AND COSMETIC USE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-03-12 | — | — | WO | disclosed |