⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405080 | 0.74 | MAPK1 (0.32) | — | |
| SCHEMBL5463684 | 0.72 | TSHR (0.36) | — | |
| SCHEMBL27277487 | 0.69 | — | — | |
| SCHEMBL12616548 | 0.68 | — | — | |
| SCHEMBL20569794 | 0.68 | — | — | |
| SCHEMBL17525873 | 0.67 | TSHR (0.35) | — | |
| SCHEMBL12939050 | 0.67 | TSHR (0.35) | — | |
| SCHEMBL17676146 | 0.65 | — | — | |
| SCHEMBL11232124 | 0.64 | TSHR (0.31) | — | |
| SCHEMBL7819387 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125808-B2 | Ionic silicone hydrogels | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-20130217620-A1 | IONIC SILICONE HYDROGELS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| EP-2252443-A1 | METHODS AND SYSTEMS FOR PROCESSING SILICONE HYDROGEL OPHTHALMIC LENSES FOR IMPROVED LENS TRANSFER | Johnson & Johnson Vision Care, Inc. (US) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009108349-A1 | METHODS AND SYSTEMS FOR PROCESSING SILICONE HYDROGEL OPHTHALMIC LENSES FOR IMPROVED LENS TRANSFER | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2009-09-03 | — | — | WO | disclosed |