Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38183 | 0.84 | — | — | |
| SCHEMBL4266363 | 0.81 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL6015163 | 0.81 | — | — | |
| SCHEMBL6015087 | 0.81 | — | — | |
| SCHEMBL5477839 | 0.81 | — | — | |
| SCHEMBL16566929 | 0.81 | ALDH1A1 (0.39) | ALDH1A1 | |
| Alcohol SCHEMBL4665688 | 0.76 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL3405084 | 0.74 | — | — | |
| SCHEMBL1245809 | 0.74 | — | — | |
| SCHEMBL17676146 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9125808-B2 | Ionic silicone hydrogels | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-20130217620-A1 | IONIC SILICONE HYDROGELS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| EP-2252443-A1 | METHODS AND SYSTEMS FOR PROCESSING SILICONE HYDROGEL OPHTHALMIC LENSES FOR IMPROVED LENS TRANSFER | Johnson & Johnson Vision Care, Inc. (US) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009108349-A1 | METHODS AND SYSTEMS FOR PROCESSING SILICONE HYDROGEL OPHTHALMIC LENSES FOR IMPROVED LENS TRANSFER | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217620-A1 | IONIC SILICONE HYDROGELS | HACD2, IGFBP2, IGFBP6 | MAPK1 421/4885ALDH1A1 3613/4885CYP2C19 1143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.