Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | LPL | P06858 | 7/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27031982 | 0.88 | FFAR1 (0.56) | FFAR1LPLLIPGDGAT1F11 | |
| SCHEMBL98872 | 0.86 | FFAR1 (0.53) | FFAR1LPLLIPGDGAT1CA1 | |
| SCHEMBL29966774 | 0.86 | FFAR1 (0.53) | FFAR1LPLLIPGDGAT1CA1 | |
| SCHEMBL2746946 | 0.86 | FFAR1 (0.53) | FFAR1LPLLIPGDGAT1CA1 | |
| SCHEMBL24609489 | 0.84 | FFAR1 (0.57) | FFAR1LPLLIPGDGAT1CA1 | |
| SCHEMBL19002004 | 0.84 | FFAR1 (0.51) | FFAR1LPLLIPGDGAT1CA1 | |
| SCHEMBL19629502 | 0.84 | FFAR1 (0.51) | FFAR1LPLLIPGDGAT1CA1 | |
| SCHEMBL1869990 | 0.81 | FFAR1 (0.60) | FFAR1LPLLIPGDGAT1CA1 | |
| SCHEMBL20759 | 0.81 | FFAR1 (0.64) | FFAR1LPLLIPGDGAT1F11 | |
| SCHEMBL14788157 | 0.80 | FFAR1 (0.58) | FFAR1LPLLIPGDGAT1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003338-A1 | COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-01-05 | — | — | WO | disclosed |