SCHEMBL98872

SCHEMBL98872

CC1(C)OB(c2cnn(COCC[Si](C)(C)C)c2)OC1(C)C

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.53
LPL P06858 7/20 0.33
LIPG Q9Y5X9 7/20 0.33
DGAT1 O75907 3/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
IRAK4 Q9NWZ3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6104470 0.91 FFAR1 (0.45) FFAR1
SCHEMBL26096629 0.87 LIPG (0.43) FFAR1LPLLIPGDGAT1CA1
SCHEMBL29966774 0.86 FFAR1 (0.53) FFAR1LPLLIPGDGAT1CA1
SCHEMBL3405330 0.86 FFAR1 (0.57) FFAR1LPLLIPGDGAT1CA1
SCHEMBL2746946 0.86 FFAR1 (0.53) FFAR1LPLLIPGDGAT1CA1
SCHEMBL24609489 0.84 FFAR1 (0.57) FFAR1LPLLIPGDGAT1CA1
SCHEMBL19629502 0.84 FFAR1 (0.51) FFAR1LPLLIPGDGAT1CA1
SCHEMBL19002004 0.84 FFAR1 (0.51) FFAR1LPLLIPGDGAT1CA1
SCHEMBL1869990 0.81 FFAR1 (0.60) FFAR1LPLLIPGDGAT1CA1
SCHEMBL20191339 0.81 DGAT1 (0.33) FFAR1DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098036-A1 2-HETEROARYL-3-OXO-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES FOR THE TREATMENT OF CANCER DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2026-04-09 US disclosed
US-12552804-B2 Tricyclic heterocycles as FGFR inhibitors INCYTE CORPORATION (US) 2026-02-17 US disclosed
EP-4688161-A1 IL4I1 INHIBITORS AND METHODS OF USE Merck Sharp & Dohme LLC (US) 2026-02-11 EP disclosed
US-12534452-B2 N-(1H-imidazol-2-yl)benzamide compound and pharmaceutical composition comprising the same as active ingredient KAINOS MEDICINE, INC. (KR) 2026-01-27 US disclosed
US-12522594-B2 2-heteroaryl-3-oxo-2,3-dihydropyridazine-4-carboxamides for the treatment of cancer DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2026-01-13 US disclosed
US-12473289-B2 Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use AMGEN INC. (US) 2025-11-18 US disclosed
US-12465653-B2 Thienoazepine immunoconjugates, and uses thereof BOLT BIOTHERAPEUTICS, INC. (US) 2025-11-11 US disclosed
US-12448396-B2 Methods of using heterocyclic compounds as Delta-5 Desaturase inhibitors AMGEN INC. (US) 2025-10-21 US disclosed
US-12428420-B2 Tricyclic heterocycles as FGFR inhibitors INCYTE CORPORATION (US) 2025-09-30 US disclosed
US-12421211-B2 Heterocyclic compounds HOFFMANN-LA ROCHE INC. (US) 2025-09-23 US disclosed
US-20070135461-A1 3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile; immune-related diseases, skin disorders, myeloid proliferative disorders, cancer INCYTE CORPORATION 2007-06-14 US disclosed
US-20070135461-A1 3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile; immune-related diseases, skin disorders, myeloid proliferative disorders, cancer INCYTE CORPORATION 2007-06-14 US disclosed
US-20070135461-A1 3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile; immune-related diseases, skin disorders, myeloid proliferative disorders, cancer INCYTE CORPORATION 2007-06-14 US disclosed
US-20070117804-A1 Imidazopyrazines as protein kinase inhibitors SCHERING CORPORATION 2007-05-24 US disclosed
US-20070105864-A1 Methods for inhibiting protein kinases SCHERING CORPORATION 2007-05-10 US disclosed
WO-2007044441-A2 USE OF PYRAZOLO [1 , 5 -A] PYRIMIDINE DERIVATIVES FOR INHIBITING PROTEIN KINASES METHODS FOR INHIBITING PROTEIN KINASES SCHERING CORPORATION (US) 2007-04-19 WO disclosed
US-20070082900-A1 Methods for inhibiting protein kinases SCHERING CORPORATION 2007-04-12 US disclosed
US-20070082900-A1 Methods for inhibiting protein kinases SCHERING CORPORATION 2007-04-12 US disclosed
US-20070072881-A1 Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors SCHERING CORPORATION 2007-03-29 US disclosed
US-20070072881-A1 Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors SCHERING CORPORATION 2007-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12421211-B2 Heterocyclic compounds F12, C1R, MRPL21 FFAR1 3384/4885LPL 4514/4885LIPG 4823/4885
US-20260098036-A1 2-HETEROARYL-3-OXO-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES FOR THE TREATMENT OF CANCER AHR, CBR1, CNR1 FFAR1 125/4885LPL 4105/4885LIPG 3906/4885
US-12448396-B2 Methods of using heterocyclic compounds as Delta-5 Desaturase inhibitors SCD5, SCD, FADS2 FFAR1 490/4885LPL 94/4885LIPG 153/4885
US-12428420-B2 Tricyclic heterocycles as FGFR inhibitors FGFR3, FGFR1, FGFR2 FFAR1 1699/4885LPL 2440/4885LIPG 1891/4885
US-20070082900-A1 Methods for inhibiting protein kinases PIM1, AURKC, PIM3 FFAR1 4804/4885LPL 4030/4885LIPG 3302/4885
US-12465653-B2 Thienoazepine immunoconjugates, and uses thereof ICOS, CYP3A5, TPH1 FFAR1 2792/4885LPL 3494/4885LIPG 3048/4885
US-20070135461-A1 3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile; immune-related diseases, skin disorders, myeloid proliferative disorders, cancer JAK1, JAK3, MAP3K4 FFAR1 3729/4885LPL 4424/4885LIPG 4299/4885
US-12552804-B2 Tricyclic heterocycles as FGFR inhibitors FGFR3, FGFR1, FGFR2 FFAR1 1016/4885LPL 2108/4885LIPG 3033/4885
US-20070117804-A1 Imidazopyrazines as protein kinase inhibitors CHEK1, CHEK2, CDKN1A FFAR1 3817/4885LPL 3695/4885LIPG 3778/4885
US-12473289-B2 Heterocyclic compounds as delta-5 desaturase inhibitors and methods of use SCD5, SCD, FADS2 FFAR1 448/4885LPL 152/4885LIPG 205/4885
US-12534452-B2 N-(1H-imidazol-2-yl)benzamide compound and pharmaceutical composition comprising the same as active ingredient IRAK4, IRAK1, IRAK2 FFAR1 442/4885LPL 2195/4885LIPG 3266/4885
US-20070105864-A1 Methods for inhibiting protein kinases PIM1, PIM2, PIM3 FFAR1 4705/4885LPL 4352/4885LIPG 4097/4885
US-20070072881-A1 Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors CDK2, CDK1, CDKN1A FFAR1 4610/4885LPL 3341/4885LIPG 3343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.