SCHEMBL3405440

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3405438	1.00	MEN1 (0.40)	MEN1KMT2ACYP2C9CYP11B1CYP11B2
	SCHEMBL3412173	0.86	CYP11B1 (0.54)	MEN1KMT2ACYP2C9CYP11B1CYP11B2
	SCHEMBL3565354	0.86	CYP11B1 (0.54)	MEN1KMT2ACYP2C9CYP11B1CYP11B2
	SCHEMBL3412170	0.86	CYP11B1 (0.54)	MEN1KMT2ACYP2C9CYP11B1CYP11B2
	SCHEMBL18017493	0.86	DHODH (0.50)	MEN1KMT2ACYP2C9CYP11B1CYP11B2
	SCHEMBL184027	0.86	DHODH (0.50)	MEN1KMT2ACYP2C9CYP11B1CYP11B2
	SCHEMBL184026	0.86	DHODH (0.50)	MEN1KMT2ACYP2C9CYP11B1CYP11B2
	SCHEMBL11388473	0.83	MAPT (0.56)	MEN1KMT2ACYP2C9MAPTALDH1A1
	SCHEMBL29254517	0.83	MAPT (0.56)	MEN1KMT2ACYP2C9MAPTALDH1A1
	SCHEMBL1012186	0.83	MAPT (0.56)	MEN1KMT2ACYP2C9MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.