Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 9/20 | 0.37 |
| ▸ | NPY1R | P25929 | 6/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.36 |
| ▸ | OTC | P00480 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 4/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15891 | 0.98 | NPY4R (0.38) | NPY4RNPY1RDPP7OTCALOX15 | |
| SCHEMBL28712062 | 0.92 | NPY4R (0.39) | NPY4RNPY1RDPP7OTCALOX15 | |
| SCHEMBL9237239 | 0.92 | NPY4R (0.39) | NPY4RNPY1RDPP7OTCALOX15 | |
| SCHEMBL288133 | 0.92 | NPY4R (0.39) | NPY4RNPY1RDPP7OTCALOX15 | |
| Hydrochloric Acid SCHEMBL8039440 | 0.90 | NPY4R (0.38) | NPY4RNPY1RDPP7OTCALOX15 | |
| SCHEMBL7061485 | 0.90 | NPY4R (0.38) | NPY4RNPY1RDPP7OTCALOX15 | |
| Hydrochloric Acid SCHEMBL8040222 | 0.90 | NPY4R (0.38) | NPY4RNPY1RDPP7OTCALOX15 | |
| SCHEMBL16194087 | 0.90 | NPY4R (0.38) | NPY4RNPY1RDPP7OTCALOX15 | |
| SCHEMBL27606498 | 0.89 | NPY4R (0.38) | NPY4RNPY1RDPP7OTCALOX15 | |
| SCHEMBL27722340 | 0.87 | NPY4R (0.37) | NPY4RNPY1RDPP7OTCALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6217851-B1 | MIXTURE OF CALCIUM, ARGININE AND BICARBONATE | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2001-04-17 | — | — | US | claimed |
| EP-4355434-A1 | ORAL CARE COMPOSITIONS COMPRISING HYDROXYAPATITE | Colgate-Palmolive Company (US) | 2024-04-24 | — | — | EP | disclosed |
| CN-117794506-A | Oral care compositions comprising hydroxyapatite | 高露洁-棕榄公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-112334197-B | Dentifrice comprising carboxylic acid or alkali metal salt thereof and free fluoride source | 葛兰素史克消费者保健（英国）知识产权有限公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-111201008-B | Dentifrice composition | 葛兰素史克消费者保健（英国）知识产权有限公司 | 2023-08-11 | — | — | CN | disclosed |
| US-20230045410-A1 | Oral Care Compositions | COLGATE-PALMOLIVE COMPANY (US) | 2023-02-09 | — | — | US | disclosed |
| WO-2023003948-A1 | ORAL CARE COMPOSITIONS COMPRISING HYDROXYAPATITE | COLGATE-PALMOLIVE COMPANY (US) | 2023-01-26 | — | — | WO | disclosed |
| EP-3082719-B1 | DENTIFRICE COMPOSITION COMPRISING SPHERICAL FUSED ALUMNIUM OXIDE PARTICLES | GlaxoSmithKline Consumer Healthcare UK IP Ltd (GB) | 2022-03-23 | — | — | EP | disclosed |
| US-11246809-B2 | Composition | GlaxosSmithKline Consumer Healthcare (UK) IP Limited (GB) | 2022-02-15 | — | — | US | disclosed |
| EP-3817828-A1 | DENTIFRICE COMPRISING CARBOXYLIC ACID OR ALKALI METAL SALT THEREOF AND A SOURCE OF FREE FLUORIDE IONS | GlaxoSmithKline Consumer Healthcare (UK) IP Limited (GB) | 2021-05-12 | — | — | EP | disclosed |
| CN-105939701-A | Dentifrice composition comprising spherical fused aluminium oxide particles | 葛兰素集团有限公司 | 2016-09-14 | — | — | CN | disclosed |
| US-20160228341-A1 | Dentifrice Composition Comprising Sintered Hydroxyapatite | GLAXO GROUP LIMITED (GB) | 2016-08-11 | — | — | US | disclosed |
| EP-3049049-A1 | DENTIFRICE COMPOSITION COMPRISING SINTERED HYDROXYAPATITE | Glaxo Group Limited (GB) | 2016-08-03 | — | — | EP | disclosed |
| EP-2249784-B1 | ORAL CARE PRODUCT AND METHODS OF USE AND MANUFACTURE THEREOF | COLGATE PALMOLIVE CO (US) | 2016-06-29 | — | — | EP | disclosed |
| WO-2015140060-A1 | NOVEL COMPOSITION | GLAXO GROUP LIMITED (GB) | 2015-09-24 | — | — | WO | disclosed |
| WO-2015091594-A1 | DENTIFRICE COMPOSITION COMPRISING SPHERICAL FUSED ALUMINIUM OXIDE PARTICLES | GLAXO GROUP LIMITED (GB) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015044156-A1 | DENTIFRICE COMPOSITION COMPRISING SINTERED HYDROXYAPATITE | GLAXO GROUP LIMITED (GB) | 2015-04-02 | — | — | WO | disclosed |
| EP-2249784-A1 | ORAL CARE PRODUCT AND METHODS OF USE AND MANUFACTURE THEREOF | Colgate-Palmolive Company (US) | 2010-11-17 | — | — | EP | disclosed |
| WO-2009099452-A1 | ORAL CARE PRODUCT AND METHODS OF USE AND MANUFACTURE THEREOF | COLGATE-PALMOLIVE COMPANY (US) | 2009-08-13 | — | — | WO | disclosed |
| US-20090202451-A1 | ORAL CARE PRODUCT AND METHODS OF USE AND MANUFACTURE THEREOF | COLGATE-PALMOLIVE COMPANY (US) | 2009-08-13 | — | — | US | disclosed |