Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29781225 | 1.00 | TAAR1 (0.39) | TAAR1CHEK1ALDH1A1PTGDR2FFAR4 | |
| SCHEMBL5820 | 0.83 | PYCR1 (0.45) | CHEK1ALDH1A1PYCR1MAPTMEN1 | |
| SCHEMBL606473 | 0.83 | PTGDR2 (0.44) | CHEK1ALDH1A1PTGDR2FFAR4PYCR1 | |
| SCHEMBL14222335 | 0.81 | TAAR1 (0.41) | TAAR1ALDH1A1PYCR1CYP1A2MAPT | |
| SCHEMBL6542411 | 0.80 | CHEK1 (0.41) | CHEK1ALDH1A1PTGDR2CYP1A2SLC6A2 | |
| SCHEMBL3406480 | 0.79 | TAAR1 (0.39) | TAAR1ALDH1A1FFAR4PYCR1MAPT | |
| SCHEMBL4951267 | 0.79 | PYCR1 (0.45) | TAAR1ALDH1A1FFAR4PYCR1MAPT | |
| SCHEMBL6911967 | 0.79 | TAAR1 (0.64) | TAAR1CHEK1ALDH1A1 | |
| SCHEMBL1569443 | 0.78 | CHEK1 (0.40) | CHEK1ALDH1A1PTGDR2CYP1A2SLC6A2 | |
| SCHEMBL29710612 | 0.78 | CHEK1 (0.40) | CHEK1ALDH1A1PTGDR2CYP1A2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288427-A1 | GPR84 ANTAGONISTS AND USES THEREOF | Liminal Biosciences Limited (GB) | 2023-12-13 | — | — | EP | disclosed |
| CN-117098757-A | GPR84 antagonists and uses thereof | 里米诺生物科学有限公司 | 2023-11-21 | — | — | CN | disclosed |
| WO-2022167457-A1 | GPR84 ANTAGONISTS AND USES THEREOF | Liminal Biosciences Limited (GB) | 2022-08-11 | — | — | WO | disclosed |
| WO-2016007736-A1 | IMIDAZOPYRAZINES AS LSD1 INHIBITORS | INCYTE CORPORATION (US) | 2016-01-14 | — | — | WO | disclosed |
| WO-2014138616-A2 | PYRAZOLE COMPOUNDS AND METHODS OF USE THEREOF | TRANSLATIONAL DRUG DEVELOPMENT, LLC (US) | 2014-09-12 | — | — | WO | disclosed |
| EP-2260032-A2 | FUNGICIDAL HETERCYCLIC COMPOUNDS | E. I. du Pont de Nemours and Company (US) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009094445-A2 | FUNGICIDAL HETERCYCLIC COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-07-30 | — | — | WO | disclosed |