Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3407739 | 0.86 | GAA (0.40) | GAAMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL3403943 | 0.84 | KMT2A (0.41) | GAAMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL3401925 | 0.78 | RAB9A (0.41) | GAAMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL544484 | 0.69 | RAB9A (0.57) | GAAMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL11614823 | 0.64 | KMT2A (0.46) | GAAMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL22198867 | 0.63 | GAA (0.41) | GAAMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL11614556 | 0.63 | KMT2A (0.57) | GAAMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL11612591 | 0.62 | KMT2A (0.48) | GAAMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL11616158 | 0.62 | KMT2A (0.43) | GAAMAPTKMT2ARAB9AMEN1 | |
| SCHEMBL11610860 | 0.62 | HSP90AA1 (0.44) | GAAMAPTKMT2ARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370260-B1 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-24 | — | — | EP | claimed |