Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | GPR39 | O43194 | 1/20 | 0.37 |
| ▸ | GCG | P01275 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL960678 | 0.93 | CNR1 (0.50) | CNR1GPR52PTGDRFYNALOX5 | |
| SCHEMBL958112 | 0.88 | GPR52 (0.48) | CNR1GPR52PTGDRFYNEPHX2 | |
| SCHEMBL960125 | 0.75 | PTGDR (0.57) | CNR1PTGDRLMNAGPR39 | |
| SCHEMBL961208 | 0.74 | CNR1 (0.49) | CNR1PTGDRLMNAGPR39 | |
| SCHEMBL959317 | 0.74 | GPR52 (0.52) | CNR1GPR52FYNMAP4K4KDR | |
| SCHEMBL1513331 | 0.69 | FYN (0.48) | GPR52PTGDRFYNMAP4K4LMNA | |
| SCHEMBL960460 | 0.68 | FYN (0.50) | GPR52FYNMAP4K4 | |
| SCHEMBL1513123 | 0.67 | FYN (0.46) | GPR52PTGDRFYNMAP4K4 | |
| SCHEMBL1513274 | 0.66 | FYN (0.49) | GPR52PTGDRFYNEPHX2MAP4K4 | |
| SCHEMBL1513288 | 0.65 | FYN (0.43) | CNR1GPR52PTGDRFYNEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2253618-A1 | COMPOUND HAVING 6-MEMBERED AROMATIC RING | Takeda Pharmaceutical Company Limited (JP) | 2010-11-24 | — | — | EP | disclosed |