Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3402912 | 1.00 | APAF1 (0.47) | APAF1MAPTL3MBTL1 | |
| Bromide SCHEMBL3404870 | 1.00 | APAF1 (0.47) | APAF1MAPTL3MBTL1 | |
| SCHEMBL12639152 | 0.99 | MAPT (0.47) | APAF1MAPTL3MBTL1 | |
| SCHEMBL15993128 | 0.99 | MAPT (0.47) | APAF1MAPTL3MBTL1 | |
| Iodide SCHEMBL15992431 | 0.97 | MAPT (0.47) | APAF1MAPTL3MBTL1 | |
| Iodide SCHEMBL1885364 | 0.97 | MAPT (0.47) | APAF1MAPTL3MBTL1 | |
| Bromide SCHEMBL1885401 | 0.94 | KDM4E (0.48) | APAF1MAPTL3MBTL1 | |
| SCHEMBL12639143 | 0.93 | KDM4E (0.49) | APAF1MAPTL3MBTL1 | |
| Iodide SCHEMBL3402593 | 0.91 | KDM4E (0.48) | APAF1MAPTL3MBTL1 | |
| Bromide SCHEMBL3406156 | 0.88 | KDM4E (0.40) | APAF1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2254871-B1 | SALTS COMPRISING ARYL-ALKYL-SUBSTITUTED IMIDAZOLIUM AND TRIAZOLIUM CATIONS AS IONIC FLUIDS | UNIV DRESDEN TECH (DE) | 2016-11-09 | — | — | EP | disclosed |
| EP-2254871-A1 | SALTS COMPRISING ARYL-ALKYL-SUBSTITUTED IMIDAZOLIUM AND TRIAZOLIUM CATIONS AS IONIC FLUIDS | Technische Universität Dresden (DE) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009095012-A1 | SALTS COMPRISING ARYL-ALKYL-SUBSTITUTED IMIDAZOLIUM AND TRIAZOLIUM CATIONS AND THE USE THEREOF | Technische Universität Dresden (DE) | 2009-08-06 | — | — | WO | disclosed |