Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CHKA | P35790 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3220803 | 0.99 | HTR6 (0.98) | HTR6MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL3223023 | 0.86 | HTR6 (1.00) | HTR6 | |
| SCHEMBL3411879 | 0.82 | HTR6 (1.00) | HTR6 | |
| Hydrochloric Acid SCHEMBL3224117 | 0.81 | HTR6 (0.98) | HTR6 | |
| SCHEMBL3204910 | 0.80 | HTR6 (1.00) | HTR6 | |
| SCHEMBL3206467 | 0.80 | HTR6 (1.00) | HTR6 | |
| Fluorobenzene SCHEMBL27780258 | 0.71 | HTR6 (0.66) | HTR6 | |
| SCHEMBL2056183 | 0.71 | CHKA (0.80) | ALDH1A1L3MBTL1CHKA | |
| Chlorobenzene SCHEMBL27758929 | 0.70 | HTR6 (0.65) | HTR6 | |
| Hydrochloric Acid SCHEMBL27780343 | 0.70 | HTR6 (0.62) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114878-B1 | 5-(HETEROCYCLYL)ALKYL-N-(ARYLSULFONYL)INDOLE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LTD (IN) | 2010-12-15 | — | — | EP | claimed |