SCHEMBL340785

SCHEMBL340785

Cc1cccc(N(CC(=O)O)CC(=O)O)c1C

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.49
ALDH1A1 P00352 3/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
LMNA P02545 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
TP53 P04637 2/20 0.42
RXRA P19793 2/20 0.41
RXRB P28702 1/20 0.41
RXRG P48443 1/20 0.41
PPARD Q03181 1/20 0.39
PPARA Q07869 1/20 0.39
MAPT P10636 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1028025 0.85 TDP1 (0.56) TDP1ALDH1A1MEN1KMT2ALMNA
SCHEMBL11414114 0.83 TDP1 (0.42) TDP1MEN1KMT2ASMN1; SMN2
SCHEMBL1027463 0.82 TDP1 (0.46) TDP1ALDH1A1MEN1KMT2ALMNA
SCHEMBL9831853 0.81 SMN1; SMN2 (0.44) TDP1ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL341369 0.79 TDP1 (0.41) TDP1ALDH1A1MEN1KMT2ALMNA
SCHEMBL342415 0.78 TDP1 (0.66) TDP1ALDH1A1
Bicarbonate SCHEMBL22188468 0.77 NR3C1 (0.55) ALDH1A1MEN1KMT2ALMNASMN1; SMN2
Malonic Acid SCHEMBL29049230 0.77 NR3C1 (0.55) ALDH1A1MEN1KMT2ALMNA
Malonic Acid SCHEMBL22188496 0.77 NR3C1 (0.55) ALDH1A1MEN1KMT2ALMNA
SCHEMBL28635231 0.76 CYP3A4 (0.47) TDP1ALDH1A1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1975707-B1 Curable composition and planographic printing plate precursor FUJIFILM CORP (JP) 2017-07-19 EP disclosed
EP-1801651-B1 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORP (JP) 2017-04-19 EP disclosed
EP-1887423-B1 Laser-decomposable resin composition and pattern-forming material using the same FUJIFILM CORP (JP) 2016-01-27 EP disclosed
EP-1431032-B1 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORP (JP) 2015-12-09 EP disclosed
EP-2039509-B1 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORP (JP) 2014-03-26 EP disclosed
US-8110337-B2 Mixture of binder, an unsaturated compound and acid generator; lithography FUJIFILM CORPORATION (JP) 2012-02-07 US disclosed
US-20120015295-A1 INFRARED-SENSITIVE COMPOSITION FOR PRINTING PLATE PRECURSORS CITICORP NORTH AMERICA, INC., AS AGENT 2012-01-19 US disclosed
EP-1862301-B1 Image recording material, planographic printing plate precursor, and planographic printing method using the same FUJIFILM CORP (JP) 2011-09-28 EP disclosed
US-8012671-B2 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-09-06 US disclosed
US-7989140-B2 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
EP-1079972-A1 IR-SENSITIVE COMPOSITION AND USE THEREOF FOR THE PREPARATION OF PRINTING PLATE PRECURSORS Kodak Polychrome Graphics Company Ltd. (US) 2001-03-07 EP disclosed
WO-2000048836-A1 IR-SENSITIVE COMPOSITION AND USE THEREOF FOR THE PREPARATION OF PRINTING PLATE PRECURSORS KODAK POLYCHROME GRAPHICS COMPANY, LTD. (US) 2000-08-24 WO disclosed
US-5942372-A COMPRISED A SPECTRAL SENSITIZER THAT SENSITIZES IN THE ULTRAVIOLET OR VISIBLE REGIONS OF THE SPECTRUM AND AN N-ARYL POLYCARBOXYLIC ACID CO-INITIATOR; VERY HIGH PHOTOSPEED AND VERY GOOD SHELF-LIFE IN COMPUTER-TO-PLATE SYSTEMS KODAK POLYCHROME GRAPHICS, LLC (US) 1999-08-24 US disclosed
US-5914215-A ELEMENT COMPRISING SUPPORT HAVING PHOTOIMAGEABLE, RADIATION SENSITIVE LAYER COMPRISING UNSATURATED COMPOUND, PHOTOINITIATOR SYSTEM COMPRISING SENSITIZER SENSITIZING IN ULTRAVIOLET OR VISIBLE REGION OF SPECTRUM, CO-INITIATOR KODAK POLYCHROME GRAPHIC, LLC (US) 1999-06-22 US disclosed
US-5888700-A NONFOGGING, SHELF LIFE KODAK POLYCHROME GRPAHICS, LLC (US) 1999-03-30 US disclosed
US-5821030-A DIRECT DIGITAL EXPOSURE; HIGH WRITING SPEED; ADHESION; ANTIFOGGING AGENTS; SHELF LIFE; USING A POLYCARBOXYLIC ACID IN THE PHOTOPOLYMERIZATION INITIATOR SYSTEM AND A BASIC COMPOUND IN THE OXYGEN BARRIER LAYER KODAK POLYCHROME GRAPHICS (US) 1998-10-13 US disclosed
US-5776655-A CONTAINING PHOTOPOLYMER EASTMAN KODAK COMPANY (US) 1998-07-07 US disclosed
EP-0795790-A2 Peel-developable lithographic printing plate EASTMAN KODAK COMPANY (US) 1997-09-17 EP disclosed
US-5629354-A Photopolymerization initiator system comprising a spectral sensitizer and a polycarboxylic acid co-initiator EASTMAN KODAK COMPANY (US) 1997-05-13 US disclosed
EP-0730201-A1 Sensitized photopolymerizable compositions and use thereof in lithographic printing plates EASTMAN KODAK COMPANY (US) 1996-09-04 EP disclosed