Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3223111 | 0.99 | HTR6 (0.98) | HTR6CHRM1KDM2B | |
| SCHEMBL3407154 | 0.92 | HTR6 (1.00) | HTR6CHRM1 | |
| Hydrochloric Acid SCHEMBL3212151 | 0.91 | HTR6 (0.98) | HTR6CHRM1 | |
| SCHEMBL3411710 | 0.85 | HTR6 (0.83) | HTR6CHRM1 | |
| Hydrochloric Acid SCHEMBL3209863 | 0.84 | HTR6 (0.81) | HTR6CHRM1 | |
| SCHEMBL3408800 | 0.81 | HTR6 (1.00) | HTR6CHRM1 | |
| Hydrochloric Acid SCHEMBL3212095 | 0.81 | HTR6 (0.98) | HTR6CHRM1 | |
| SCHEMBL3411372 | 0.80 | HTR6 (1.00) | HTR6CHRM1 | |
| SCHEMBL3413817 | 0.79 | HTR6 (0.82) | HTR6CHRM1 | |
| SCHEMBL3411022 | 0.79 | HTR6 (1.00) | HTR6CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114878-B1 | 5-(HETEROCYCLYL)ALKYL-N-(ARYLSULFONYL)INDOLE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LTD (IN) | 2010-12-15 | — | — | EP | claimed |