Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.59 |
| ▸ | KCNA3 | P22001 | 11/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2890650 | 0.95 | MEN1 (0.67) | MEN1KMT2AALDH1A1SLC6A9KCNA3 | |
| SCHEMBL2888614 | 0.92 | MEN1 (0.62) | MEN1KMT2AALDH1A1SLC6A9KCNA3 | |
| SCHEMBL3413864 | 0.91 | KMT2A (0.60) | MEN1KMT2AALDH1A1SLC6A9KCNA3 | |
| SCHEMBL2887079 | 0.88 | MEN1 (0.71) | MEN1KMT2AALDH1A1SLC6A9KCNA3 | |
| SCHEMBL2890714 | 0.87 | MEN1 (0.70) | MEN1KMT2AALDH1A1SLC6A9KCNA3 | |
| SCHEMBL2891736 | 0.86 | KMT2A (0.59) | MEN1KMT2AALDH1A1SLC6A9KCNA3 | |
| SCHEMBL2888977 | 0.86 | MEN1 (0.63) | MEN1KMT2AALDH1A1SLC6A9KCNA3 | |
| SCHEMBL2886762 | 0.85 | MEN1 (0.62) | MEN1KMT2AALDH1A1SLC6A9KCNA3 | |
| SCHEMBL2883643 | 0.85 | SLC6A9 (0.81) | MEN1KMT2AALDH1A1SLC6A9KCNA3 | |
| SCHEMBL2883437 | 0.84 | MEN1 (0.61) | MEN1KMT2AALDH1A1SLC6A9KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261210-B1 | 3-SUBSTITUTED SULFONYL PIPERAZINE DERIVATIVE | MSD KK (JP) | 2014-10-22 | — | — | EP | disclosed |
| EP-2261210-A1 | 3-SUBSTITUTED SULFONYL PIPERAZINE DERIVATIVE | Banyu Pharmaceutical Co., Ltd. (JP) | 2010-12-15 | — | — | EP | disclosed |