⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3434802 | 0.78 | — | — | |
| SCHEMBL26574 | 0.73 | — | — | |
| SCHEMBL20591244 | 0.73 | — | — | |
| SCHEMBL226473 | 0.73 | — | — | |
| SCHEMBL776535 | 0.73 | — | — | |
| Ethylene SCHEMBL6657822 | 0.70 | — | — | |
| SCHEMBL3408235 | 0.70 | — | — | |
| Fluoride SCHEMBL21137227 | 0.70 | — | — | |
| SCHEMBL1501396 | 0.70 | — | — | |
| Ammonia Solution, Strong SCHEMBL17800250 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338937-B1 | 1-[3-(4-Hydroxy-phenyl)-1-hydoxy-1-propyl]-2-(amino-alkyleneoxy)-benzene derivatives, process for their preparation and their therapeutical use | SYNTHELABO (FR) | 1993-12-08 | — | — | EP | claimed |
| US-5144029-A | Calcium antagonist | DELALANDE S.A. (FR) | 1992-09-01 | — | — | US | claimed |
| EP-0338937-A2 | 1-[3-(4-Hydroxy-phenyl)-1-hydoxy-1-propyl]-2-(amino-alkyleneoxy)-benzene derivatives, process for their preparation and their therapeutical use | SYNTHELABO (FR) | 1989-10-25 | — | — | EP | claimed |
| JP-1311076-A | — | — | None | — | — | JP | disclosed |
| EP-4121415-B1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIV PALACKEHO (CZ) | 2024-02-07 | — | — | EP | disclosed |
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |
| WO-2021185391-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2021-09-23 | — | — | WO | disclosed |
| EP-2266977-B1 | 2,4-di[(hetero)arylamino]-pyrimidine derivatives as zap-70 and/or syk inhibitors | NOVARTIS AG (CH) | 2014-05-14 | — | — | EP | disclosed |
| US-8283356-B2 | 2,4- Di(hetero)-arylamino-pyrimidine derivatives as ZAP-70 and/or SYK inhibitors | NOVARTIS AG (CH) | 2012-10-09 | — | — | US | disclosed |
| EP-2266977-A1 | 2,4-di[(hetero)arylamino]-pyrimidine derivatives as zap-70 and/or syk inhibitors | Novartis AG (CH) | 2010-12-29 | — | — | EP | disclosed |
| US-20100152182-A1 | 2,4- Di(hetero)-arylamino-pyrimidine Derivatives as ZAP-70 and/or SYK inhibitors | NOVARTIS AG (CH) | 2010-06-17 | — | — | US | disclosed |
| WO-2000024719-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2000-05-04 | — | — | WO | disclosed |
| EP-0338937-B1 | 1-[3-(4-Hydroxy-phenyl)-1-hydoxy-1-propyl]-2-(amino-alkyleneoxy)-benzene derivatives, process for their preparation and their therapeutical use | SYNTHELABO (FR) | 1993-12-08 | — | — | EP | disclosed |
| US-5144029-A | Calcium antagonist | DELALANDE S.A. (FR) | 1992-09-01 | — | — | US | disclosed |
| US-5144029-A | Calcium antagonist | DELALANDE S.A. (FR) | 1992-09-01 | — | — | US | disclosed |
| US-5017572-A | CALCIUM ANTAGONIST | DELALANDE S.A. (FR) | 1991-05-21 | — | — | US | disclosed |
| US-5017572-A | CALCIUM ANTAGONIST | DELALANDE S.A. (FR) | 1991-05-21 | — | — | US | disclosed |
| JP-H01311076-A | 1-(3-(4HYDROXYPHENYL)-1-HYDROXY1-PROPYL) BENZENE DERIVATIVE | DELALANDE SA | 1989-12-15 | — | — | JP | disclosed |
| EP-0338937-A2 | 1-[3-(4-Hydroxy-phenyl)-1-hydoxy-1-propyl]-2-(amino-alkyleneoxy)-benzene derivatives, process for their preparation and their therapeutical use | SYNTHELABO (FR) | 1989-10-25 | — | — | EP | disclosed |
| EP-0338937-A2 | 1-[3-(4-Hydroxy-phenyl)-1-hydoxy-1-propyl]-2-(amino-alkyleneoxy)-benzene derivatives, process for their preparation and their therapeutical use | SYNTHELABO (FR) | 1989-10-25 | — | — | EP | disclosed |