Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365301 | 0.86 | SIGMAR1 (0.30) | SIGMAR1 | |
| SCHEMBL2177486 | 0.69 | EGLN1 (0.42) | EGLN1 | |
| SCHEMBL2176563 | 0.68 | EGLN1 (0.41) | EGLN1 | |
| SCHEMBL12408994 | 0.62 | EGLN1 (0.40) | EGLN1 | |
| SCHEMBL1965690 | 0.61 | EGLN1 (0.44) | EGLN1 | |
| SCHEMBL1971349 | 0.59 | SCD (0.49) | — | |
| SCHEMBL2177885 | 0.58 | SCD (0.48) | SIGMAR1 | |
| SCHEMBL1974270 | 0.58 | SCD (0.66) | — | |
| SCHEMBL1986750 | 0.58 | SCD (0.40) | EGLN1 | |
| SCHEMBL1986109 | 0.57 | SCD (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010037225-A1 | HETEROAROMATIC COMPOUNDS AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-04-08 | — | — | WO | disclosed |