Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 13/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2344486 | 1.00 | MC4R (0.48) | MC4RTP53TSHRMEN1KMT2A | |
| SCHEMBL3014389 | 0.94 | MC4R (0.45) | MC4RTP53TSHRMEN1KMT2A | |
| SCHEMBL31388217 | 0.81 | MC4R (0.54) | MC4RCYP3A4MAPK1KCNQ2GAA | |
| SCHEMBL390826 | 0.81 | MC4R (0.54) | MC4RCYP3A4MAPK1KCNQ2GAA | |
| SCHEMBL442668 | 0.81 | MC4R (0.54) | MC4RCYP3A4MAPK1KCNQ2GAA | |
| SCHEMBL17871701 | 0.81 | MC4R (0.54) | MC4RCYP3A4MAPK1KCNQ2GAA | |
| SCHEMBL31128130 | 0.81 | MC4R (0.54) | MC4RCYP3A4MAPK1KCNQ2GAA | |
| SCHEMBL1964089 | 0.81 | MC4R (0.54) | MC4RCYP3A4MAPK1KCNQ2GAA | |
| SCHEMBL3407639 | 0.81 | MC4R (0.42) | MC4RABCC8CYP3A4SLC22A1ABCC3 | |
| Hydrochloric Acid SCHEMBL17871800 | 0.80 | MC4R (0.53) | MC4RCYP3A4MAPK1KCNQ2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177221-A1 | Process for the preparation of substantially optically pure Repaglinide and precursors thereof | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2010-04-21 | — | — | EP | claimed |
| EP-2177221-A1 | Process for the preparation of substantially optically pure Repaglinide and precursors thereof | Krka Tovarna Zdravil, D.D., Novo Mesto (SI) | 2010-04-21 | — | — | EP | disclosed |