Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3413681 | 0.77 | HSD17B10 (0.35) | MGAMGAASIMGAM2MAPK1 | |
| SCHEMBL12826838 | 0.77 | HSD17B10 (0.35) | MGAMGAASIMGAM2MAPK1 | |
| SCHEMBL12746001 | 0.77 | TSHR (0.38) | MGAMGAASIMGAM2MAPK1 | |
| SCHEMBL1462621 | 0.75 | ALDH1A1 (0.43) | MAPK1MEN1KMT2A | |
| SCHEMBL11859635 | 0.74 | MAPK1 (0.38) | MAPK1MEN1KMT2ATSHRPTGES | |
| SCHEMBL1462907 | 0.73 | MGAM (0.31) | MGAMGAASIMGAM2MAPK1 | |
| SCHEMBL1462910 | 0.73 | MGAM (0.31) | MGAMGAASIMGAM2MAPK1 | |
| SCHEMBL29235155 | 0.68 | HSD17B10 (0.41) | MGAMGAASIMGAM2MEN1 | |
| SCHEMBL2999438 | 0.68 | HSD17B10 (0.38) | MGAMGAASIMGAM2MEN1 | |
| SCHEMBL8411060 | 0.68 | ALDH1A1 (0.36) | MAPK1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260041-A2 | CEPHALOTAXUS ESTERS, METHODS OF SYNTHESIS, AND USES THEREOF | Sloan Kettering Institute For Cancer Research (US) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009148654-A2 | CEPHALOTAXUS ESTERS, METHODS OF SYNTHESIS, AND USES THEREOF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2009-12-10 | — | — | WO | disclosed |