SCHEMBL3409013

SCHEMBL3409013

O=S(=O)(c1ccc(F)cc1)n1cc(Cl)c2cc(CN3CCNCC3)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 18/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3218951 0.99 HTR6 (0.98) HTR6
SCHEMBL3204910 0.88 HTR6 (1.00) HTR6
SCHEMBL3409914 0.87 HTR6 (1.00) HTR6
Hydrochloric Acid SCHEMBL3222700 0.86 HTR6 (0.98) HTR6
Hydrochloric Acid SCHEMBL3221004 0.86 HTR6 (0.84) HTR6
Hydrochloric Acid SCHEMBL3221009 0.84 HTR6 (0.72) HTR6
Fluorobenzene SCHEMBL27758927 0.79 HTR6 (0.65) HTR6
SCHEMBL3206467 0.79 HTR6 (1.00) HTR6
Hydrochloric Acid SCHEMBL27780441 0.77 HTR6 (0.62) HTR6
SCHEMBL3411879 0.75 HTR6 (1.00) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2114878-B1 5-(HETEROCYCLYL)ALKYL-N-(ARYLSULFONYL)INDOLE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS SUVEN LIFE SCIENCES LTD (IN) 2010-12-15 EP claimed