Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27818530 | 0.98 | CYP1A2 (0.46) | TDP1CYP1A2PAOXCA12CA2 | |
| SCHEMBL7216698 | 0.89 | — | — | |
| SCHEMBL31591139 | 0.89 | ALDH1A1 (0.37) | TDP1CYP1A2LMNACHRM1HSD17B10 | |
| SCHEMBL29052233 | 0.89 | ALDH1A1 (0.37) | TDP1CYP1A2LMNACHRM1HSD17B10 | |
| Methane SCHEMBL28946775 | 0.87 | — | — | |
| SCHEMBL30776079 | 0.82 | ALDH1A1 (0.32) | — | |
| SCHEMBL9120653 | 0.82 | CHRM2 (0.33) | CHRM1 | |
| SCHEMBL9596546 | 0.82 | CYP1A2 (0.44) | TDP1CYP1A2PAOXCA12CA2 | |
| SCHEMBL29958708 | 0.81 | PAOX (0.38) | TDP1PAOXNPSR1POLB | |
| SCHEMBL5681764 | 0.80 | CYP1A2 (0.42) | TDP1CYP1A2PAOXCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269744-B | Methods for preparing Toll-like receptor modulator compounds | 吉利德科学公司 | 2024-10-18 | — | — | CN | claimed |
| CN-114269744-A | Methods for preparing Toll-like receptor modulator compounds | 吉利德科学公司 | 2022-04-01 | — | — | CN | claimed |
| CN-113552241-A | Method for determining residual content of 4-methylpiperazine-1-formate genotoxic impurities in zopiclone | 江苏天士力帝益药业有限公司 | 2021-10-26 | — | — | CN | claimed |
| CN-101248048-B | Imidazole based LXR modulators | EXELIXIS INC | 2013-08-28 | — | — | CN | claimed |
| EP-1503980-A2 | SUBSTITUTED HYDROXYETHYLAMINES | Elan Pharmaceuticals, Inc. (US) | 2005-02-09 | — | — | EP | claimed |
| WO-2003072535-A2 | SUBSTITUTED HYDROXYETHYLAMINES | ELAN PHARMACEUTICALS, INC. (US) | 2003-09-04 | — | — | WO | claimed |
| EP-4615842-A1 | TOLL-LIKE RECEPTOR 7 AGONISTS AS IMMUNE-STIMULATORS TO ELICIT THE INNATE ANTITUMOR IMMUNITY | Merck Patent GmbH (DE) | 2025-09-17 | — | — | EP | disclosed |
| CN-119371422-A | Methods for preparing Toll-like receptor modulator compounds | 吉利德科学公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-114269744-B | Methods for preparing Toll-like receptor modulator compounds | 吉利德科学公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-118420697-A | C-12-Pyxinol derivative, preparation method and application thereof | 烟台大学 | 2024-08-02 | — | — | CN | disclosed |
| EP-4384493-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd (KY) | 2024-06-19 | — | — | EP | disclosed |
| WO-2024100093-A1 | TOLL-LIKE RECEPTOR 7 AGONISTS AS IMMUNE-STIMULATORS TO ELICIT THE INNATE ANTITUMOR IMMUNITY | MERCK PATENT GMBH (DE) | 2024-05-16 | — | — | WO | disclosed |
| EP-4367111-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-05-15 | — | — | EP | disclosed |
| EP-1238974-A1 | HETEROCYCLE DERIVATIVES AND DRUGS | Nippon Shinyaku Co., Ltd. (JP) | 2002-09-11 | — | — | EP | disclosed |
| EP-0580633-B1 | HETEROCYCLIC AMINES USEFUL IN THE THERAPY OF ASTHMA AND INFLAMMATION OF THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA (IT) | 1998-06-17 | — | — | EP | disclosed |
| EP-0580633-A1 | HETEROCYCLIC AMINES USEFUL IN THE THERAPY OF ASTHMA AND INFLAMMATION OF THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1994-02-02 | — | — | EP | disclosed |
| WO-1992018478-A1 | HETEROCYCLIC AMINES USEFUL IN THE THERAPY OF ASTHMA AND INFLAMMATION OF THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-10-29 | — | — | WO | disclosed |
| EP-0096870-B1 | ESTER OF METRONIDAZOLE WITH N,N-DIMETHYLGLYCINE AND ACID ADDITION SALT THEREOF | A/S Dumex (Dumex Ltd.) (DK) | 1986-10-01 | — | — | EP | disclosed |
| US-4482722-A | FOR PARENTERAL ADMINISTRATION | A/S DUMEX (DUMEX LTD.) (DK) | 1984-11-13 | — | — | US | disclosed |
| EP-0096870-A1 | Ester of metronidazole with N,N-dimethylglycine and acid addition salt thereof | A/S Dumex (Dumex Ltd.) (DK) | 1983-12-28 | — | — | EP | disclosed |