Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3411771 | 0.96 | MET (0.54) | MET | |
| SCHEMBL1656789 | 0.88 | MET (0.54) | MET | |
| SCHEMBL3407734 | 0.86 | MET (0.58) | MET | |
| SCHEMBL1659655 | 0.84 | MET (0.56) | MET | |
| SCHEMBL1659722 | 0.83 | MET (0.53) | MET | |
| SCHEMBL1661084 | 0.82 | MET (0.51) | MET | |
| SCHEMBL1659704 | 0.82 | MET (0.49) | MET | |
| SCHEMBL1659338 | 0.82 | MET (0.73) | MET | |
| SCHEMBL1661490 | 0.81 | MET (0.54) | MET | |
| SCHEMBL1659629 | 0.81 | MET (0.54) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265614-A1 | IMIDAZO [1,2-B]PYRIDAZINE DERIVATIVES FOR THE TREATMENT OF C-MET TYROSINE KINASE MEDIATED DISEASE | Novartis AG (CH) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009106577-A1 | IMIDAZO [1,2-B] PYRIDAZINE DERIVATIVES FOR THE TREATMENT OF C-MET TYROSINE KINASE MEDIATED DISEASE | NOVARTIS AG (CH) | 2009-09-03 | — | — | WO | disclosed |