Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250864 | 0.84 | MAPK14 (0.34) | MAPK14LMNAKMT2AALDH1A1GAA | |
| SCHEMBL253756 | 0.68 | MEN1 (0.36) | MAPK14KMT2AALDH1A1GAA | |
| SCHEMBL3407742 | 0.66 | KDR (0.43) | — | |
| SCHEMBL11914746 | 0.63 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL2600116 | 0.62 | ALDH1A1 (0.46) | LMNAKMT2AALDH1A1GAA | |
| SCHEMBL24634836 | 0.60 | ALDH1A1 (0.43) | LMNAKMT2AALDH1A1GAA | |
| SCHEMBL20233507 | 0.60 | ALDH1A1 (0.43) | LMNAKMT2AALDH1A1GAA | |
| SCHEMBL4199616 | 0.59 | MAPK14 (0.46) | MAPK14 | |
| SCHEMBL17229785 | 0.58 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL27108463 | 0.58 | MAPK14 (0.47) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003338-A1 | COMBINATION OF A cMET INHIBITOR AND AN ANTIBODY TO HGF AND/OR cMET | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-01-05 | — | — | WO | disclosed |