Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28998050 | 0.91 | NPC1 (0.52) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL31079637 | 0.89 | POLB (0.53) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7270115 | 0.85 | NPC1 (0.54) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9490613 | 0.85 | NPC1 (0.50) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10974072 | 0.85 | NPC1 (0.50) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10972741 | 0.85 | NPC1 (0.50) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL21605311 | 0.85 | NPC1 (0.50) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28711480 | 0.84 | NPC1 (0.55) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL11666229 | 0.84 | NPC1 (0.44) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13496587 | 0.82 | SLC1A3 (0.54) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925674-A | Fullerene-based electron transport material with Lewis base group and application thereof | 四川轻化工大学 | 2023-04-07 | — | — | CN | claimed |
| CN-115925674-A | Fullerene-based electron transport material with Lewis base group and application thereof | 四川轻化工大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-115925674-A | Fullerene-based electron transport material with Lewis base group and application thereof | 四川轻化工大学 | 2023-04-07 | — | — | CN | disclosed |
| EP-2257540-A2 | IMPROVED PROCESS FOR EPROSARTAN INTERMEDIATE | Hetero Research Foundation (IN) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009122421-A2 | IMPROVED PROCESS FOR EPROSARTAN INTERMEDIATE | HETERO RESEARCH FOUNDATION (IN) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009084028-A2 | IMPROVED PROCESS FOR MANUFACTURING ANHYDROUS (E)-3-[2-BUTYL-1- {(4-CARBOXYPHENYL) METHYL}-1H-IMIDAZOLE-5-YL]-(THIOPHEN-2- YLMETHYL)PROP-2-ENOIC ACID METHANE SULFONATE | NEULAND LABORATORIES LTD (IN) | 2009-07-09 | — | — | WO | disclosed |
| CN-1093128-C | Process for preparing eprosartan | SMITHKLINE BEECHAM CORP (US) | 2002-10-23 | — | — | CN | disclosed |
| US-6294675-B1 | CHEMICAL INTERMEDIATE | SMITHKLINE BEECHAM CORPORATION | 2001-09-25 | — | — | US | disclosed |
| CN-1247538-A | Process for preparing eprosartan | SMITHKLINE BEECHAM CORP (US) | 2000-03-15 | — | — | CN | disclosed |