Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31079637 | 0.85 | POLB (0.53) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3409571 | 0.85 | NPC1 (0.56) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7270115 | 0.82 | NPC1 (0.54) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL21605311 | 0.82 | NPC1 (0.50) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10974072 | 0.82 | NPC1 (0.50) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL10972741 | 0.82 | NPC1 (0.50) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL1455603 | 0.81 | POLB (0.53) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28711480 | 0.81 | NPC1 (0.55) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL28998050 | 0.81 | NPC1 (0.52) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13496587 | 0.79 | SLC1A3 (0.54) | NPC1RAB9ASLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114349735-B | O-GlcNAc transferase inhibitors, and preparation method and application thereof | 中国药科大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-116162085-A | Novel O-GlcNAc transferase inhibitor and application thereof | 重庆医科大学 | 2023-05-26 | — | — | CN | disclosed |
| EP-0532621-A1 | AMIDE LINKED PYRIDYLE-BENZOIC ACID DERIVATIVES FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991018883-A1 | AMIDE LINKED PYRIDYLE-BENZOIC ACID DERIVATIVES FOR TREATING LEUKOTRIENE-RELATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |