SCHEMBL3409687

SCHEMBL3409687

CC(C)c1ccc(S(=O)(=O)n2ccc3cc(CN4CCNCC4)ccc32)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3219374 0.99 HTR6 (0.98) HTR6
SCHEMBL3221120 0.88 HTR6 (1.00) HTR6
Hydrochloric Acid SCHEMBL3409658 0.88 HTR6 (0.98) HTR6
SCHEMBL3407441 0.86 HTR6 (1.00) HTR6
Hydrochloric Acid SCHEMBL3215761 0.85 HTR6 (0.98) HTR6
SCHEMBL3222022 0.78 HTR6 (1.00) HTR6
SCHEMBL3411022 0.78 HTR6 (1.00) HTR6
SCHEMBL947751 0.77 HTR6 (0.63) HTR6
Hydrochloric Acid SCHEMBL3219449 0.77 HTR6 (0.98) HTR6
SCHEMBL3209765 0.76 HTR6 (0.83) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2114878-B1 5-(HETEROCYCLYL)ALKYL-N-(ARYLSULFONYL)INDOLE COMPOUNDS AND THEIR USE AS 5-HT6 LIGANDS SUVEN LIFE SCIENCES LTD (IN) 2010-12-15 EP claimed