Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL6 | Q9H5J4 | 18/20 | 0.56 |
| ▸ | ELOVL3 | Q9HB03 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889042 | 0.87 | ELOVL6 (0.62) | ELOVL6ELOVL3TP53 | |
| SCHEMBL2889039 | 0.87 | ELOVL6 (0.62) | ELOVL6ELOVL3TP53 | |
| SCHEMBL2891035 | 0.74 | ELOVL6 (0.70) | ELOVL6ELOVL3 | |
| SCHEMBL2891037 | 0.74 | ELOVL6 (0.70) | ELOVL6ELOVL3 | |
| SCHEMBL2883519 | 0.74 | ELOVL6 (0.70) | ELOVL6ELOVL3 | |
| SCHEMBL2883518 | 0.74 | ELOVL6 (0.70) | ELOVL6ELOVL3 | |
| SCHEMBL16150873 | 0.73 | JAK2 (0.41) | PTPN2PTPN1PTPN6 | |
| SCHEMBL792679 | 0.73 | CHRM2 (0.57) | — | |
| SCHEMBL30994163 | 0.73 | CHRM2 (0.57) | — | |
| SCHEMBL2890236 | 0.73 | CHRM2 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261210-A1 | 3-SUBSTITUTED SULFONYL PIPERAZINE DERIVATIVE | Banyu Pharmaceutical Co., Ltd. (JP) | 2010-12-15 | — | — | EP | disclosed |