Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859560 | 0.86 | TDP1 (0.33) | NAALAD2KDM4ETDP1L3MBTL1NPC1 | |
| SCHEMBL2863660 | 0.84 | KDM4E (0.34) | KDM4ETDP1L3MBTL1HKDC1PDE10A | |
| SCHEMBL2866246 | 0.84 | ALDH1A1 (0.34) | L3MBTL1PDE10APTGDR2ALDH1A1LMNA | |
| SCHEMBL2863098 | 0.84 | NTRK1 (0.37) | NPC1RAB9AMLYCDPTGDR2MEN1 | |
| SCHEMBL2867053 | 0.83 | CYSLTR1 (0.31) | KDM4ETDP1L3MBTL1HKDC1PDE10A | |
| SCHEMBL2866439 | 0.83 | RXFP1 (0.33) | PDE10AALDH1A1 | |
| SCHEMBL3402152 | 0.82 | NAALAD2 (0.37) | NAALAD2 | |
| SCHEMBL2857237 | 0.81 | NTRK1 (0.34) | MLYCD | |
| SCHEMBL2860764 | 0.81 | SCN9A (0.30) | — | |
| SCHEMBL3409088 | 0.73 | NAALAD2 (0.38) | NAALAD2CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370260-B1 | AZOLES AS MALONYL-COA DECARBOXYLASE INHIBITORS USEFUL AS METABOLIC MODULATORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-11-24 | — | — | EP | claimed |