Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 4/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL963328 | 1.00 | MEN1 (0.49) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL963327 | 1.00 | MEN1 (0.49) | MEN1LMNACYP2D6HRH1SCN1A | |
| Bromide SCHEMBL3491155 | 0.98 | MEN1 (0.47) | MEN1LMNACYP2D6HRH1SCN1A | |
| Bromide SCHEMBL3491157 | 0.98 | MEN1 (0.47) | MEN1LMNACYP2D6HRH1SCN1A | |
| Oxalic Acid SCHEMBL4747187 | 0.93 | MEN1 (0.46) | MEN1LMNACYP2D6HRH1SCN1A | |
| Oxalic Acid SCHEMBL4747189 | 0.93 | MEN1 (0.46) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL8424963 | 0.90 | DRD2 (0.40) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL8424962 | 0.90 | DRD2 (0.40) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL4180834 | 0.90 | HRH1 (0.56) | MEN1LMNACYP2D6HRH1SCN1A | |
| SCHEMBL10360054 | 0.89 | MEN1 (0.38) | MEN1LMNACYP2D6HRH1SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2261205-A1 | METHOD OF PRODUCING (S)-3-(1-CYANO-1,1-DIPHENYLMETHYL)-PYRROLIDINE | Kaneka Corporation (JP) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009125426-A2 | NOVEL PROCESS FOR THE PREPARATION OF (3SM-[2-(2 J-DIHYDRO-5- BENZOFURANYLϊETHYL]-α.α -DIPHENYL-3-PYRROLIDINEACETAMIDE HYDROBROMIDE | NEULAND LABORATORIES LTD (IN) | 2009-10-15 | — | — | WO | disclosed |
| WO-2009125430-A2 | IMPROVED PROCESS FOR PRODUCING DARIFENACIN | MATRIX LABORATOIRES LIMITED (IN) | 2009-10-15 | — | — | WO | disclosed |
| EP-0900787-B1 | PROCESS FOR PREPARING PYRROLIDINE DERIVATIVES | KANEKA CORP (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-6005119-A | Process for preparing pyrrolidine derivatives | KANEKA CORPORATION (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0900787-A1 | PROCESS FOR PREPARING PYRROLIDINE DERIVATIVES | KANEKA CORPORATION (JP) | 1999-03-10 | — | — | EP | disclosed |
| EP-0505376-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LTD (GB) | 1994-12-07 | — | — | EP | disclosed |
| US-5340831-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-08-23 | — | — | US | disclosed |
| EP-0388054-B1 | Pyrrolidine derivatives | PFIZER LTD (GB) | 1993-11-03 | — | — | EP | disclosed |
| US-5233053-A | Pyrrolidine derivatives | PFIZER INC. (US) | 1993-08-03 | — | — | US | disclosed |
| EP-0505376-A1 | MUSCARINIC RECEPTOR ANTAGONISTS. | PFIZER LTD (GB) | 1992-09-30 | — | — | EP | disclosed |
| US-5096890-A | PYRROLIDINE DERIVATIVES | PFIZER INC. (US) | 1992-03-17 | — | — | US | disclosed |
| WO-1991009013-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1991-06-27 | — | — | WO | disclosed |
| EP-0388054-A1 | Pyrrolidine derivatives | Pfizer Limited (GB) | 1990-09-19 | — | — | EP | disclosed |