SCHEMBL3410286

SCHEMBL3410286

COCCOCCOC(=O)CCc1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.35
LMNA P02545 1/20 0.35
ALOX5 P09917 1/20 0.34
GAA P10253 4/20 0.33
MAOB P27338 3/20 0.33
MAOA P21397 2/20 0.33
KMT2A Q03164 2/20 0.32
ACHE P22303 1/20 0.32
GSK3B P49841 1/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL100821 1.00 KDM4E (0.35) KDM4ELMNAALOX5GAAMAOB
SCHEMBL3290975 1.00 KDM4E (0.35) KDM4ELMNAALOX5GAAMAOB
SCHEMBL3288191 0.97 ALOX5 (0.36) KDM4ELMNAALOX5GAAMAOB
SCHEMBL7525719 0.90 GAA (0.38) ALOX5GAAMAOBMAOAKMT2A
SCHEMBL3413677 0.90 ALOX5 (0.41) KDM4ELMNAALOX5GAAMAOB
SCHEMBL100778 0.90 ALOX5 (0.41) KDM4ELMNAALOX5GAAMAOB
SCHEMBL101256 0.90 ALOX5 (0.41) KDM4ELMNAALOX5GAAMAOB
SCHEMBL3287819 0.90 ALOX5 (0.41) KDM4ELMNAALOX5GAAMAOB
SCHEMBL9870753 0.89 CNR1 (0.40) KDM4EGAAMAOBMAOAKMT2A
SCHEMBL9615371 0.89 GAA (0.34) ALOX5GAAMAOBMAOAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2267523-A2 Stabilized electrochromic media BASF SE (DE) 2010-12-29 EP claimed
US-7595011-B2 One or more solvents, one or more materials which are functional elements of electrochromic devices, one or more ultraviolet light absorbers selected from hydroxyphenylbenzotriazoles and tris-aryl-s-triazines, and one or more NH or N-alkyl hindered amine light stabilizers; discoloration inhibition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-09-29 US claimed
CN-100520551-C Electrochromic medium composition, preparation method thereof and electroactive device comprising same CIBA SC HOLDING AG (CH) 2009-07-29 CN claimed
CN-1985214-A Stable electrochromic medium CIBA SC HOLDING AG (CH) 2007-06-20 CN claimed
US-20060007519-A1 Stabilized electrochromic media CIBA SPECIALTY CHEMICALS CORP. 2006-01-12 US claimed
EP-1896550-B1 STABILIZED ELECTROCHROMIC MEDIA BASF SE (DE) 2013-08-14 EP disclosed
EP-2267523-A2 Stabilized electrochromic media BASF SE (DE) 2010-12-29 EP disclosed
US-7595011-B2 One or more solvents, one or more materials which are functional elements of electrochromic devices, one or more ultraviolet light absorbers selected from hydroxyphenylbenzotriazoles and tris-aryl-s-triazines, and one or more NH or N-alkyl hindered amine light stabilizers; discoloration inhibition CIBA SPECIALTY CHEMICALS CORPORATION (US) 2009-09-29 US disclosed
CN-100520551-C Electrochromic medium composition, preparation method thereof and electroactive device comprising same CIBA SC HOLDING AG (CH) 2009-07-29 CN disclosed
CN-1985214-A Stable electrochromic medium CIBA SC HOLDING AG (CH) 2007-06-20 CN disclosed
US-20060007519-A1 Stabilized electrochromic media CIBA SPECIALTY CHEMICALS CORP. 2006-01-12 US disclosed