Dimebutic Acid

Dimebutic Acid

SCHEMBL3411633

CCC(C)(C)C(=O)O.CCN(C)C

nearest known ligand 0.40

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Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 12/20 0.40
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
ACLY P53396 1/20 0.34
CYP2D6 P10635 2/20 0.33
CYP2C19 P33261 2/20 0.33
HIF1A Q16665 1/20 0.33
CYP1A2 P05177 1/20 0.33
ACACB O00763 1/20 0.33
ACACA Q13085 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimebutic Acid SCHEMBL47533 0.87
Dimebutic Acid SCHEMBL28444780 0.84
Dimebutic Acid SCHEMBL1055427 0.84
Dimebutic Acid SCHEMBL1961089 0.84
Dimebutic Acid SCHEMBL1962006 0.84
Dimebutic Acid SCHEMBL25275531 0.84
Dimebutic Acid SCHEMBL20139427 0.84
Dimebutic Acid SCHEMBL1176300 0.84
Dimebutic Acid SCHEMBL8383027 0.84
Dimebutic Acid SCHEMBL27959638 0.84 TSHR (0.42) RIPK1TSHRALDH1A1ACLYCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2265617-B1 SOLVENTS BIONIQS LTD (GB) 2014-07-02 EP claimed
EP-2265617-A1 SOLVENTS Bioniqs Limited (GB) 2010-12-29 EP claimed
WO-2009034329-A1 SOLVENTS BIONIQS LIMITED (GB) 2009-03-19 WO claimed
EP-2265617-B1 SOLVENTS BIONIQS LTD (GB) 2014-07-02 EP disclosed
EP-2265617-A1 SOLVENTS Bioniqs Limited (GB) 2010-12-29 EP disclosed
WO-2009034329-A1 SOLVENTS BIONIQS LIMITED (GB) 2009-03-19 WO disclosed