Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.46 |
| ▸ | HMGCR | P04035 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GGT1 | P19440 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6054302 | 0.88 | ALDH1A1 (0.53) | TSHRALDH1A1TET2HMGCRCHRM1 | |
| SCHEMBL15841566 | 0.82 | ALDH1A1 (0.47) | TSHRALDH1A1TET2HMGCRCHRM1 | |
| SCHEMBL3951357 | 0.78 | TSHR (0.43) | TSHRALDH1A1TET2HMGCRCHRM1 | |
| SCHEMBL6054231 | 0.78 | ALDH1A1 (0.56) | TSHRALDH1A1TET2HMGCRCHRM1 | |
| SCHEMBL6441636 | 0.77 | ALDH1A1 (0.47) | TSHRALDH1A1TET2HMGCRCHRM1 | |
| SCHEMBL253116 | 0.77 | ALDH1A1 (0.47) | TSHRALDH1A1TET2HMGCRCHRM1 | |
| Bicarbonate SCHEMBL26105671 | 0.74 | TSHR (0.41) | TSHRALDH1A1TET2HMGCRCHRM1 | |
| SCHEMBL2899117 | 0.73 | — | — | |
| SCHEMBL85014 | 0.73 | TSHR (0.42) | TSHRALDH1A1TET2HMGCRCHRM1 | |
| SCHEMBL79613 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276776-B1 | CATALYST FOR PRODUCING AN ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE AND METHOD FOR PRODUCING AN ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE USING THE SAME | SAMSUNG GENERAL CHEMICALS CO (KR) | 2006-11-02 | — | — | EP | claimed |
| US-5459116-A | Magnesium, titanium, halogen and hydroxyalkyl ester compounds; stereospecific, bulk density; polyethylene | SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) | 1995-10-17 | — | — | US | claimed |
| US-7803785-B2 | Gemcitabine prodrugs, pharmaceutical compositions and uses thereof | XENOPORT, INC. (US) | 2010-09-28 | — | — | US | disclosed |
| US-20100016254-A1 | GEMCITABINE PRODRUGS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | XENOPORT, INC. (US) | 2010-01-21 | — | — | US | disclosed |
| US-7608602-B2 | Gemcitabine prodrugs, pharmaceutical compositions and uses thereof | XENOPORT, INC. (US) | 2009-10-27 | — | — | US | disclosed |
| US-20080021208-A1 | Gemcitabine Prodrugs, Pharmaceutical Compositions and Uses Thereof | XENOPORT, INC. (US) | 2008-01-24 | — | — | US | disclosed |
| US-7265096-B2 | Gemcitabine prodrugs, pharmaceutical compositions and uses thereof | XENOPORT, INC. (US) | 2007-09-04 | — | — | US | disclosed |
| EP-1421122-B1 | CATALYST FOR POLYMERIZATION AND COPOLYMERIZATION OF ETHYLENE | SAMSUNG GENERAL CHEMICALS CO (KR) | 2006-06-14 | — | — | EP | disclosed |
| EP-1401882-B1 | CATALYST FOR POLYMERIZATION AND COPOLYMERIZATION OF ETHYLENE | SAMSUNG GENERAL CHEMICALS CO (KR) | 2006-06-14 | — | — | EP | disclosed |
| EP-1567169-A2 | GEMCITABINE PRODRUGS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Xenoport, Inc. (US) | 2005-08-31 | — | — | EP | disclosed |
| EP-1421122-A4 | CATALYST FOR POLYMERIZATION AND COPOLYMERIZATION OF ETHYLENE | SAMSUNG GENERAL CHEMICALS CO (KR) | 2005-05-04 | — | — | EP | disclosed |
| US-20040023792-A1 | Catalyst for polymerization and copolymerization of ethylene | HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) | 2004-02-05 | — | — | US | disclosed |
| US-20030032551-A1 | Catalyst for polymerization and copolymerization of ethylene | HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) | 2003-02-13 | — | — | US | disclosed |
| WO-2003000747-A1 | CATALYST FOR POLYMERIZATION AND COPOLYMERIZATION OF ETHYLENE | SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000745-A1 | CATALYST FOR POLYMERIZATION AND COPOLYMERIZATION OF ETHYLENE | SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) | 2003-01-03 | — | — | WO | disclosed |
| EP-0607191-B1 | DYE-IMAGE RECEIVING ELEMENT FOR USE ACCORDING TO THERMAL DYE SUBLIMATION TRANSFER | AGFA GEVAERT NV (BE) | 1996-03-20 | — | — | EP | disclosed |
| US-5459116-A | Magnesium, titanium, halogen and hydroxyalkyl ester compounds; stereospecific, bulk density; polyethylene | SAMSUNG GENERAL CHEMICALS CO., LTD. (KR) | 1995-10-17 | — | — | US | disclosed |
| US-5376618-A | Receiver layer contains copolyester from diols, dicarboxylic acids and long chain alkyl hydroxy-carboxylic acids | AGFA-GEVAERT, N.V. (BE) | 1994-12-27 | — | — | US | disclosed |
| EP-0481130-B1 | Thermal dye sublimation transfer receiving element | AGFA GEVAERT NV (BE) | 1994-06-08 | — | — | EP | disclosed |
| EP-0481130-A1 | Thermal dye sublimation transfer receiving element | AGFA-GEVAERT N.V. (BE) | 1992-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016254-A1 | GEMCITABINE PRODRUGS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | TYMP, GDA, GCG | TSHR 4354/4885ALDH1A1 1615/4885TET2 3091/4885 |
| US-20080021208-A1 | Gemcitabine Prodrugs, Pharmaceutical Compositions and Uses Thereof | TYMP, GDA, GCG | TSHR 4354/4885ALDH1A1 1615/4885TET2 3091/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.