Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1058083 | 0.79 | SHBG (0.32) | — | |
| SCHEMBL4222183 | 0.74 | SMN1; SMN2 (0.34) | ACEEPHX1 | |
| SCHEMBL1502025 | 0.69 | — | — | |
| SCHEMBL2923689 | 0.69 | SHBG (0.41) | EPHX1 | |
| SCHEMBL3170657 | 0.66 | SHBG (0.37) | — | |
| SCHEMBL3901953 | 0.66 | — | — | |
| SCHEMBL12760529 | 0.66 | — | — | |
| SCHEMBL1502476 | 0.64 | — | — | |
| SCHEMBL3901923 | 0.63 | — | — | |
| SCHEMBL10773183 | 0.63 | CYP1A2 (0.39) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231595-B1 | PHENYL ACETIC ACID DERIVATIVES AS INFLAMMATION MODULATORS | AMGEN INC (US) | 2014-04-23 | — | — | EP | disclosed |
| US-8183293-B2 | Phenyl acetic acid derivatives | AMGEN INC. (US) | 2012-05-22 | — | — | US | disclosed |
| EP-2231595-A1 | PHENYL ACETIC ACID DERIVATIVES AS INFLAMMATION MODULATORS | Amgen, Inc (US) | 2010-09-29 | — | — | EP | disclosed |
| US-20090275659-A1 | Phenyl acetic acid derivatives as inflammation modulators | AMGEN INC. (US) | 2009-11-05 | — | — | US | disclosed |
| WO-2009085177-A1 | PHENYL ACETIC ACID DERIVATIVES AS INFLAMMATION MODULATORS | AMGEN INC. (US) | 2009-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275659-A1 | Phenyl acetic acid derivatives as inflammation modulators | NFKBIA, HCAR2, NFATC1 | ACE 680/4885EPHX1 1148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.