Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.66 |
| ▸ | CTSK | P43235 | 13/20 | 0.66 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412444 | 1.00 | CTSS (0.66) | CTSSCTSKHRH3 | |
| SCHEMBL1632248 | 0.88 | CTSS (0.72) | CTSSCTSK | |
| SCHEMBL1630383 | 0.87 | CTSS (0.77) | CTSSCTSK | |
| SCHEMBL1630387 | 0.87 | CTSS (0.77) | CTSSCTSK | |
| SCHEMBL1631110 | 0.87 | CTSS (0.77) | CTSSCTSK | |
| SCHEMBL1630265 | 0.86 | CTSS (0.75) | CTSSCTSK | |
| SCHEMBL1629848 | 0.85 | CTSS (0.71) | CTSSCTSK | |
| SCHEMBL1629861 | 0.84 | CTSS (0.71) | CTSSCTSK | |
| SCHEMBL1629505 | 0.82 | CTSS (0.68) | CTSSCTSK | |
| SCHEMBL3412915 | 0.81 | CTSS (0.67) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178873-B1 | 6-PHENYL-1H-IMIDAZO[4,5-C]PYRIDINE-4-CARBONITRILE DERIVATIVES AS CATHEPSIN INHIBITORS | ORGANON NV (NL) | 2010-12-22 | — | — | EP | disclosed |