Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1406187 | 0.88 | CYP3A4 (0.43) | CYP3A4CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL1406189 | 0.83 | CYP1A2 (0.50) | CYP3A4CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL187988 | 0.82 | CYP1A2 (0.35) | CYP3A4CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL8390711 | 0.82 | CYP1A2 (0.36) | CYP3A4CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL30962428 | 0.81 | CYP1A2 (0.57) | CYP3A4CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL27322 | 0.81 | CYP1A2 (0.57) | CYP3A4CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL9328172 | 0.79 | CYP1A2 (0.35) | CYP3A4CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL20408076 | 0.77 | CYP3A4 (0.43) | CYP3A4CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL12633334 | 0.76 | CYP3A4 (0.48) | CYP3A4CYP2C9CYP2C19CYP1A2TSHR | |
| SCHEMBL14599163 | 0.75 | CYP3A4 (0.51) | CYP3A4CYP2C9CYP2C19CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9017475-B2 | Metal pigment composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-04-28 | — | — | US | disclosed |
| US-20100000445-A1 | Metal Pigment Composition | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2010-01-07 | — | — | US | disclosed |