Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8390711 | 0.88 | CYP1A2 (0.36) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9328276 | 0.85 | SMN1; SMN2 (0.38) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL187988 | 0.85 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9351780 | 0.82 | CYP2C9 (0.42) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL29130830 | 0.81 | POLB (0.34) | CYP1A2CYP2C9CYP2C19RXRAPPARG | |
| SCHEMBL7147241 | 0.81 | HSP90AA1 (0.36) | RXRAPPARG | |
| SCHEMBL1406187 | 0.80 | CYP3A4 (0.43) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL3412467 | 0.79 | CYP3A4 (0.42) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9328498 | 0.77 | ALDH1A1 (0.34) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL20408076 | 0.74 | CYP3A4 (0.43) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312915-A2 | Process for making cyclic aryl chlorophosphites | ETHYL CORPORATION (US) | 1989-04-26 | — | — | EP | claimed |
| EP-0357048-B1 | Process for transhalogenating a halophosphorus compound with hydrogen fluoride | ALBEMARLE CORP (US) | 1994-09-28 | — | — | EP | disclosed |
| EP-0358985-B1 | Method of transhalogenating a halophosphorus compound with fluoride | ETHYL CORP (US) | 1994-03-16 | — | — | EP | disclosed |
| EP-0312790-B1 | Process for transhalogenating a halophosphorus compound with fluoride | ETHYL CORP (US) | 1993-11-18 | — | — | EP | disclosed |
| US-5136075-A | Process for transhalogenating a halophosphorus compound with fluoride | ETHYL CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| US-5061818-A | Fluorination with metal or ammonium fluoride in presence of pyridine halide salt | ETHYL CORPORATION (US) | 1991-10-29 | — | — | US | disclosed |
| US-5049691-A | Process for transhalogenating a halophosphorous compound with anhydrous hydrogen fluoride | ETHYL CORPORATION (US) | 1991-09-17 | — | — | US | disclosed |
| US-5008417-A | Haloalkylation process | ETHYL CORPORATION (US) | 1991-04-16 | — | — | US | disclosed |
| US-4958034-A | DISCOLORATION INHIBITION; REACTION OF OLEFIN AND MALEIC ANHYDRIDE IN ARYLFLUOROPHOSPHITE PRESENCE | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |
| US-4929745-A | Transhalogenation of halophosphorus compounds | EHTYL CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0358985-A1 | Method of transhalogenating a halophosphorus compound with fluoride | ETHYL CORPORATION (US) | 1990-03-21 | — | — | EP | disclosed |
| US-4910324-A | Using a metal or ammonium fluoride | ETHYL CORPORATION (US) | 1990-03-20 | — | — | US | disclosed |
| EP-0357048-A2 | Process for transhalogenating a halophosphorus compound with hydrogen fluoride | ALBEMARLE CORPORATION (US) | 1990-03-07 | — | — | EP | disclosed |
| EP-0353598-A2 | Transhalogenation of halophosphorus compounds | ETHYL CORPORATION (US) | 1990-02-07 | — | — | EP | disclosed |
| EP-0312790-A2 | Process for transhalogenating a halophosphorus compound with fluoride | ETHYL CORPORATION (US) | 1989-04-26 | — | — | EP | disclosed |