Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2896828 | 0.87 | SLC6A2 (0.39) | SLC6A2SLC6A4IDO1TDO2CTSA | |
| SCHEMBL28463867 | 0.82 | SLC6A4 (0.46) | SLC6A2SLC6A4IDO1TDO2ALDH1A1 | |
| SCHEMBL14587086 | 0.81 | IDO1 (0.42) | SLC6A2SLC6A4IDO1TDO2ALDH1A1 | |
| SCHEMBL10766473 | 0.76 | S1PR1 (0.39) | ALDH1A1HTTNPSR1SMN1; SMN2GABRG2 | |
| SCHEMBL8851108 | 0.75 | IDO1 (0.60) | SLC6A2SLC6A4IDO1TDO2CTSA | |
| SCHEMBL612957 | 0.75 | IDO1 (0.40) | SLC6A2SLC6A4IDO1TDO2CTSA | |
| SCHEMBL1525071 | 0.73 | IDO1 (0.39) | SLC6A2SLC6A4IDO1TDO2CTSA | |
| SCHEMBL18426652 | 0.72 | ALDH1A1 (0.43) | SLC6A2SLC6A4IDO1TDO2CTSA | |
| SCHEMBL13779026 | 0.72 | IDO1 (0.38) | SLC6A2SLC6A4IDO1TDO2CTSA | |
| SCHEMBL27836347 | 0.72 | IDO1 (0.38) | SLC6A2SLC6A4IDO1TDO2CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262805-A1 | POLYSUBSTITUTED DERIVATIVES OF 2-HETEROARYL-6-PHENYL-IMIDAZO[L,2-A] PYRIDINES, AND PREPARATION AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009144395-A1 | POLYSUBSTITUTED DERIVATIVES OF 2-HETEROARYL-6-PHENYL-IMIDAZO[L,2- Α] PYRIDINES, AND PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-12-03 | — | — | WO | disclosed |