Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.61 |
| ▸ | FABP3 | P05413 | 6/20 | 0.62 |
| ▸ | TERT | O14746 | 3/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | PPARG | P37231 | 3/20 | 0.61 |
| ▸ | PPARD | Q03181 | 3/20 | 0.61 |
| ▸ | PPARA | Q07869 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | FABP4 | P15090 | 2/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | F7 | P08709 | 2/20 | 0.61 |
| ▸ | F3 | P13726 | 2/20 | 0.61 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28018195 | 1.00 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| SCHEMBL7045888 | 0.98 | FABP3 (0.65) | FABP3TERTPTPN1PPARGPPARD | |
| SCHEMBL1626315 | 0.98 | FABP3 (0.65) | FABP3TERTPTPN1PPARGPPARD | |
| SCHEMBL4133929 | 0.98 | FABP3 (0.65) | FABP3TERTPTPN1PPARGPPARD | |
| Hydrochloric Acid SCHEMBL25963 | 0.96 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Iodide SCHEMBL6695071 | 0.96 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Propane SCHEMBL480215 | 0.96 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Hydrochloric Acid SCHEMBL35815 | 0.96 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Water SCHEMBL3915284 | 0.96 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Water SCHEMBL3915280 | 0.96 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114514012-A | External preparation for skin | 株式会社高丝 | 2022-05-17 | — | — | CN | disclosed |
| WO-2021075413-A1 | EXTERNAL PREPARATION FOR SKIN | 株式会社コーセー | 2021-04-22 | — | — | WO | disclosed |
| EP-2263699-B1 | SOLUTION COMPOSITION FOR CONTACT LENSES | MENICON CO LTD (JP) | 2014-03-12 | — | — | EP | disclosed |
| EP-2263699-A1 | SOLUTION COMPOSITION FOR CONTACT LENSES | Menicon Co., Ltd. (JP) | 2010-12-22 | — | — | EP | disclosed |
| US-7364723-B1 | Liquid preparation for contact lenses | MENICON CO., LTD. (JP) | 2008-04-29 | — | — | US | disclosed |
| EP-0958836-B1 | Contact lens disinfecting solution | MENICON CO LTD (JP) | 2005-03-23 | — | — | EP | disclosed |
| EP-1214883-B1 | LIQUID PREPARATION FOR CONTACT LENSES | MENICON CO LTD (JP) | 2003-11-26 | — | — | EP | disclosed |
| EP-1214883-A1 | LIQUID PREPARATION FOR CONTACT LENSES | MENICON CO., LTD. (JP) | 2002-06-19 | — | — | EP | disclosed |
| US-6121327-A | MIXTURE OF NITROGEN DISINFECTANT, ALCOHOL AND BIS(2-HYDROXYETHYL)IMINOTRI(HYDROXYMETHYL)METHANE | MENICON CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| EP-0958836-A2 | Contact lens disinfecting solution | Menicon Co., Ltd. (JP) | 1999-11-24 | — | — | EP | disclosed |