Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 6/20 | 0.62 |
| ▸ | TERT | O14746 | 3/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.61 |
| ▸ | PPARG | P37231 | 3/20 | 0.61 |
| ▸ | PPARD | Q03181 | 3/20 | 0.61 |
| ▸ | PPARA | Q07869 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | FABP4 | P15090 | 2/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | F7 | P08709 | 2/20 | 0.61 |
| ▸ | F3 | P13726 | 2/20 | 0.61 |
| ▸ | GMNN | O75496 | 1/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL3915284 | 1.00 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| SCHEMBL4133929 | 0.98 | FABP3 (0.65) | FABP3TERTPTPN1PPARGPPARD | |
| SCHEMBL1626315 | 0.98 | FABP3 (0.65) | FABP3TERTPTPN1PPARGPPARD | |
| SCHEMBL7045888 | 0.98 | FABP3 (0.65) | FABP3TERTPTPN1PPARGPPARD | |
| Iodide SCHEMBL6695071 | 0.96 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Propane SCHEMBL480215 | 0.96 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Bromide SCHEMBL3414482 | 0.96 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Hydrochloric Acid SCHEMBL35815 | 0.96 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Hydrochloric Acid SCHEMBL25963 | 0.96 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD | |
| Bromide SCHEMBL28018195 | 0.96 | FABP3 (0.62) | FABP3TERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7510005-B2 | Acrylate, methylacrylate polymerizable monomer; ammonium persulfate/N,N,N',N'-tetramethylethylene diamine redox initiator; dioctadecyldimethylammonium chloride antistatic agent; heat fluid system to decrease the risk of sparking and fire | CHEVRON U.S.A. INC. (US) | 2009-03-31 | — | — | US | claimed |
| US-20080223576-A1 | Acrylate, methylacrylate polymerizable monomer; ammonium persulfate/N,N,N',N'-tetramethylethylene diamine redox initiator; dioctadecyldimethylammonium chloride antistatic agent; heat fluid system to decrease the risk of sparking and fire | CHEVRON U.S.A. INC. (US) | 2008-09-18 | — | — | US | claimed |
| EP-1948903-A1 | CONTROLLING PRESSURE AND STATIC CHARGE WITHIN A WELLBORE | Chevron U.S.A. Inc. (US) | 2008-07-30 | — | — | EP | claimed |
| WO-2008057102-A1 | CONTROLLING PRESSURE AND STATIC CHARGE WITHIN A WELLBORE | CHEVRON U.S.A. INC. (US) | 2008-05-15 | — | — | WO | claimed |
| US-20070114034-A1 | Controlling pressure and static charge build up within an annular volume of a wellbore | CHEVRON U.S.A. INC. (US) | 2007-05-24 | — | — | US | claimed |
| US-7510005-B2 | Acrylate, methylacrylate polymerizable monomer; ammonium persulfate/N,N,N',N'-tetramethylethylene diamine redox initiator; dioctadecyldimethylammonium chloride antistatic agent; heat fluid system to decrease the risk of sparking and fire | CHEVRON U.S.A. INC. (US) | 2009-03-31 | — | — | US | disclosed |
| US-20080223576-A1 | Acrylate, methylacrylate polymerizable monomer; ammonium persulfate/N,N,N',N'-tetramethylethylene diamine redox initiator; dioctadecyldimethylammonium chloride antistatic agent; heat fluid system to decrease the risk of sparking and fire | CHEVRON U.S.A. INC. (US) | 2008-09-18 | — | — | US | disclosed |
| EP-1948903-A1 | CONTROLLING PRESSURE AND STATIC CHARGE WITHIN A WELLBORE | Chevron U.S.A. Inc. (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2008057102-A1 | CONTROLLING PRESSURE AND STATIC CHARGE WITHIN A WELLBORE | CHEVRON U.S.A. INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| US-20070114034-A1 | Controlling pressure and static charge build up within an annular volume of a wellbore | CHEVRON U.S.A. INC. (US) | 2007-05-24 | — | — | US | disclosed |
| EP-0136478-B1 | POWDERED CARPET TREATING COMPOSITIONS | UNION CARBIDE CORPORATION (US) | 1988-03-02 | — | — | EP | disclosed |
| US-4526583-A | Hydrated sodium borate, hydrated metal aluminosilicate, cationic quaternary ammonium salt, antistatic agents | UNION CARBIDE CORPORATION (US) | 1985-07-02 | — | — | US | disclosed |
| US-4141841-A | Antistatic, fabric-softening detergent additive | THE PROCTER & GAMBLE COMPANY (US) | 1979-02-27 | — | — | US | disclosed |
| EP-0000416-A1 | Antistatic, fabric-softening detergent additive | THE PROCTER & GAMBLE COMPANY (US) | 1979-01-24 | — | — | EP | disclosed |
| US-4118525-A | WATER-INSOLUBLE SUBSTRATE, QUATERNARY AMMONIUM, ANTISTATIC COMPOUND, DISPERSION INHIBITOR | THE PROCTER & GAMBLE COMPANY (US) | 1978-10-03 | — | — | US | disclosed |
| US-4113630-A | LAUNDERING, FABRIC SOFTENERS, ANTISTATIC AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1978-09-12 | — | — | US | disclosed |
| US-4095946-A | Article for cleaning and conditioning fabrics | THE PROCTER & GAMBLE COMPANY (US) | 1978-06-20 | — | — | US | disclosed |
| US-3993573-A | SMECTITE CLAY, CATIONIC ANTISTATIC AGENTS AND ACIDIC COMPATIBILIZING AGENTS | THE PROCTER & GAMBLE COMPANY (US) | 1976-11-23 | — | — | US | disclosed |
| US-3954632-A | SMECTITE CLAY, QUATERNARY AMMONIUM ANTISTATIC AGENT, CARBOXYLIC ACID | THE PROCTER & GAMBLE COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
| US-3936537-A | QUATERNARY AMMONIUM COMPOUND | THE PROCTER & GAMBLE COMPANY (US) | 1976-02-03 | — | — | US | disclosed |