Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2565042 | 0.80 | TAAR1 (0.38) | TAAR1GAAMEN1ALDH1A1KMT2A | |
| SCHEMBL30004999 | 0.80 | TAAR1 (0.38) | TAAR1GAAMEN1ALDH1A1KMT2A | |
| SCHEMBL4651500 | 0.77 | TAAR1 (0.32) | TAAR1GAAMEN1ALDH1A1KMT2A | |
| SCHEMBL21355814 | 0.76 | TAAR1 (0.38) | TAAR1GAAMEN1ALDH1A1KMT2A | |
| SCHEMBL30949557 | 0.73 | CYP1A2 (0.33) | TAAR1GAA | |
| SCHEMBL21356261 | 0.73 | TAAR1 (0.32) | TAAR1GAAMEN1ALDH1A1KMT2A | |
| SCHEMBL29384390 | 0.73 | TAAR1 (0.32) | TAAR1GAAMEN1ALDH1A1KMT2A | |
| SCHEMBL3416805 | 0.73 | CYP1A2 (0.33) | — | |
| SCHEMBL4652922 | 0.72 | MEN1 (0.33) | TAAR1GAAMEN1ALDH1A1KMT2A | |
| SCHEMBL3265635 | 0.72 | TAAR1 (0.68) | TAAR1GAAKMT2ACNR1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2265616-A1 | FURO-AND THIENO[3,2-C]PYRIDINES | OSI Pharmaceuticals, Inc. (US) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009100282-A1 | FURO-AND THIENO[3,2-C] PYRIDINES | OSI PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |