SCHEMBL3415

SCHEMBL3415

[O]c1cccc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.53
HSD17B10 Q99714 4/20 0.53
CYP2A6 P11509 3/20 0.53
TSHR P16473 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
CYP1A2 P05177 4/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
HPGD P15428 2/20 0.48
CYP3A4 P08684 1/20 0.48
KEAP1 Q14145 1/20 0.48
HPRT1 P00492 1/20 0.48
NR4A1 P22736 1/20 0.46
NR4A2 P43354 1/20 0.46
NR4A3 Q92570 1/20 0.46
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 1/20 0.44
PAX8 Q06710 1/20 0.44
HIF1A Q16665 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8196971 0.97 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL10427678 0.97 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL6410405 0.97 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL3165939 0.85 HPRT1 (0.67) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL60533 0.85 HPRT1 (0.67) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL298203 0.79 PTPN1 (0.46) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL82006 0.79 ALDH1A1 (0.54) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL14353799 0.79 ALDH1A1 (0.54) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL14353793 0.78 ALDH1A1 (0.52) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL14353989 0.78 ALDH1A1 (0.58) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 46375 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6432995-B1 None US claimed
CN-111433231-B Method for producing styrene resin and styrene resin molded body 出光兴产株式会社 2024-07-16 CN claimed
CN-113278153-B Polymer, process for producing the same and process for depolymerizing the same 北京大学 2024-07-12 CN claimed
EP-4396166-A1 2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF TUMORS Istituto Pasteur Italia (IT) 2024-07-10 EP claimed
CN-118317956-A Bis (hetero) aryl thioether oxadiazines as fungicidal compounds 拜耳公司 2024-07-09 CN claimed
WO-2024143336-A1 HYDRAZIDE COMPOUND AND AGRICULTURAL/HORTICULTURAL BACTERICIDAL AGENT 日本曹達株式会社 2024-07-04 WO claimed
WO-2024143338-A1 FIVE-MEMBERED HETEROARYL COMPOUND AND AGRICULTURAL AND HORTICULTURAL BACTERICIDE 日本曹達株式会社 2024-07-04 WO claimed
EP-4392408-A1 PYRAZINE COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2024-07-03 EP claimed
CN-118271241-A Axis chiral nitrogen-containing heteroaromatic ring polydentate ligand, preparation method and application thereof 华东理工大学 2024-07-02 CN claimed
CN-114380817-B Benzimidazolo 2-amino-1, 3, 4-thiadiazole compound, preparation method and pharmaceutical application thereof 中国医学科学院药物研究所 2024-06-21 CN claimed
US-3981858-A AZO DYES SANDOZ LTD. (CH) 1976-09-21 US claimed
US-3980430-A CATIONIC DYE, HALOGENATED HYDROCARBON BAYER AKTIENGESELLSCHAFT (DT) 1976-09-14 US claimed
US-3966715-A 1,2,4-TRIAZINE-5-ONES BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US claimed
US-3962215-A PHOSPHORYLATION, ACYLATION, WATER, ACID CHLORIDE, ALCOHOL AMERICAN HOME PRODUCTS CORPORATION (US) 1976-06-08 US claimed
US-3956339-A 4-Pyridinio-5-pyrazolone salts, process for their preparation and their use FUJI PHOTO FILM CO., LTD. (JA) 1976-05-11 US claimed
US-3956177-A Rhodium hydroformylation catalyst PHILLIPS PETROLEUM COMPANY (US) 1976-05-11 US claimed
US-3956264-A Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component BAYER AKTIENGESELLSCHAFT (DT) 1976-05-11 US claimed
US-3948877-A POLYACRYLONITRILE, ACID MODIFIED POLYESTERS OR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-04-06 US claimed
US-3932400-A CARDIOVASCULAR DISORDERS, ANTIARRHYTHMIA AGENTS SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-01-13 US claimed
US-3930866-A MAGENTA FUJI PHOTO FILM CO., LTD. (JA) 1976-01-06 US claimed