Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 7/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21391631 | 0.91 | PDK2 (0.59) | ALOX5PDK2ESR2ALDH1A1HPGD | |
| SCHEMBL20941772 | 0.91 | PDK2 (0.59) | ALOX5PDK2ESR2ALDH1A1HPGD | |
| SCHEMBL31668465 | 0.91 | PDK2 (0.59) | ALOX5PDK2ESR2ALDH1A1HPGD | |
| SCHEMBL30003384 | 0.91 | PDK2 (0.59) | ALOX5PDK2ESR2ALDH1A1HPGD | |
| SCHEMBL789268 | 0.91 | PDK2 (0.59) | ALOX5PDK2ESR2ALDH1A1HPGD | |
| SCHEMBL30511893 | 0.91 | PDK2 (0.59) | ALOX5PDK2ESR2ALDH1A1HPGD | |
| SCHEMBL3446444 | 0.87 | PDK2 (0.53) | ALOX5PDK2ESR2BACE1BCL2L1 | |
| SCHEMBL20218919 | 0.84 | PDK2 (0.53) | ALOX5PDK2ESR2ALDH1A1HPGD | |
| SCHEMBL29638158 | 0.84 | PDK2 (0.53) | ALOX5PDK2ESR2ALDH1A1HPGD | |
| SCHEMBL30697106 | 0.84 | PDK2 (0.53) | ALOX5PDK2ESR2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8349533-B2 | Resist lower-layer composition containing thermal acid generator, resist lower layer film-formed substrate, and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-01-08 | — | — | US | disclosed |
| US-20100119970-A1 | Resist lower-layer composition containing thermal acid generator, resist lower layer film-formed substrate, and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100119970-A1 | Resist lower-layer composition containing thermal acid generator, resist lower layer film-formed substrate, and patterning process | SCO2, CA1, LCT | ALOX5 175/4885PDK2 3757/4885ESR2 3986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.