Resiquimod

Resiquimod

SCHEMBL34159

CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

TLR7TLR8

The experimentally established mechanism targets of Resiquimod. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR7 known ✓ Q9NYK1 19/20 1.00
TLR8 known ✓ Q9NR97 12/20 1.00
NUDT1 P36639 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resiquimod SCHEMBL29358122 1.00 TLR7 (1.00) TLR7TLR8NUDT1
Resiquimod SCHEMBL21352711 1.00 TLR7 (1.00) TLR7TLR8NUDT1
Resiquimod SCHEMBL2266073 0.99 TLR7 (0.98) TLR7TLR8NUDT1
Resiquimod SCHEMBL2262583 0.99 TLR7 (0.98) TLR7TLR8NUDT1
SCHEMBL24880278 0.94 TLR7 (0.88) TLR7TLR8NUDT1
Resiquimod SCHEMBL22158700 0.93 TLR7 (0.86) TLR7TLR8NUDT1
Resiquimod SCHEMBL17190806 0.93 TLR7 (0.86) TLR7TLR8NUDT1
SCHEMBL6718996 0.92 TLR7 (0.84) TLR7TLR8NUDT1
SCHEMBL20199817 0.91 TLR7 (1.00) TLR7TLR8NUDT1
SCHEMBL5454764 0.90 TLR7 (0.82) TLR7TLR8NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 21397 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3993771-B1 SONODYNAMIC THERAPY INNOVATION ULSTER LTD (GB) 2026-05-27 EP claimed
US-20260139063-A1 PRE-MEDICATION AND IMPROVED TREATMENT REGIMEN MONTA BIOSCIENCES APS (DK) 2026-05-21 US claimed
EP-4743119-A1 FORMULATED AND/OR CO-FORMULATED LIPOSOME COMPOSITIONS CONTAINING TGFB ANTAGONIST PRODRUGS USEFUL IN THE TREATMENT OF CANCER AND METHODS THEREOF Nammi Therapeutics, Inc. (US) 2026-05-20 EP claimed
CN-122031668-A Formulations for neoplasia vaccines 博德研究所 2026-05-15 CN claimed
EP-3641771-B1 COMPOSITIONS COMPRISING CRYSTALLINE RESIQUIMOD MONOSULFATE ANHYDRATE SALT OR OTHER RESIQUIMOD CRYSTALLINE SALTS OR OTHER CRYSTALLINE SALTS OF 1H-IMIDAZO-[4,5-C]-QUINOLINE DERIVATIVES FOR THE TREATMENT OF CANCER BIRDIE BIOPHARMACEUTICALS INC (KY) 2026-05-13 EP claimed
CN-122005785-A Method for identifying HIV patients susceptible to therapy with GP 120V 3 glycan-directed antibodies 吉利德科学公司 2026-05-12 CN claimed
US-12622922-B2 Compositions and methods for metal containing formulations capable of modulating immune response THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2026-05-12 US claimed
EP-4735045-A2 OXAZAPHOSPHORINE ANTIBODY DRUG CONJUGATES AND METHODS OF USE La Life Products, LLC (US) 2026-05-06 EP claimed
US-20260116918-A1 NOVEL IMMUNOTHERAPY AGAINST SEVERAL TUMORS INCLUDING NEURONAL AND BRAIN TUMORS IMMATICS BIOTECHNOLOGIES GMBH (DE) 2026-04-30 US claimed
US-20260115313-A1 ANTIBODY-CONJUGATED LIPOSOME HIGHFIELD BIOPHARMACEUTICALS CORPORATION (CN) 2026-04-30 US claimed
US-6039969-A TH2 CELL MEDIATED DISEASE BACTERICIDES, ANTICARCINOGENIC AGENTS 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-03-21 US claimed
EP-0942724-A2 GEL FORMULATIONS FOR TOPICAL DRUG DELIVERY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-09-22 EP claimed
EP-0938315-A1 IMMUNE RESPONSE MODIFIER COMPOUNDS FOR TREATMENT OF TH2 MEDIATED AND RELATED DISEASES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-09-01 EP claimed
US-5939090-A OF THE DRUG 4-AMINO-2-ETHOXYMETHYL-.ALPHA.,.ALPHA.-DIMETHYL-1H-IMIDAZO(4,5 -C)QUINOLINE-1-ETHANOL, WHICH WHEN APPLIED TOPICALLY INDUCES CYTOKINES, SUCH AS INTERFERON AND TUMOR NECROSIS FACTOR, 3M INNOVATIVE PROPERTIES COMPANY (US) 1999-08-17 US claimed
EP-0582581-B1 1-SUBSTITUTED, 2-SUBSTITUTED 1H-IMIDAZO[4,5-c]QUINOLIN-4-AMINES MINNESOTA MINING & MFG (US) 1999-05-06 EP claimed
WO-1998024436-A2 GEL FORMULATIONS FOR TOPICAL DRUG DELIVERY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-06-11 WO claimed
WO-1998017279-A1 IMMUNE RESPONSE MODIFIER COMPOUNDS FOR TREATMENT OF TH2 MEDIATED AND RELATED DISEASES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-30 WO claimed
EP-0636031-B1 VACCINE ADJUVANT MINNESOTA MINING & MFG (US) 1996-09-04 EP claimed
EP-0636031-A1 VACCINE ADJUVANT. MINNESOTA MINING & MFG (US) 1995-02-01 EP claimed
WO-1993020847-A1 VACCINE ADJUVANT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-10-28 WO claimed