SCHEMBL24880278

SCHEMBL24880278

CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(O)O

nearest known ligand 0.88

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 19/20 0.88
TLR8 Q9NR97 13/20 0.88
NUDT1 P36639 1/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resiquimod SCHEMBL29358122 0.94 TLR7 (1.00) TLR7TLR8NUDT1
Resiquimod SCHEMBL21352711 0.94 TLR7 (1.00) TLR7TLR8NUDT1
Resiquimod SCHEMBL34159 0.94 TLR7 (1.00) TLR7TLR8NUDT1
Resiquimod SCHEMBL2266073 0.93 TLR7 (0.98) TLR7TLR8NUDT1
Resiquimod SCHEMBL2262583 0.93 TLR7 (0.98) TLR7TLR8NUDT1
SCHEMBL6718996 0.92 TLR7 (0.84) TLR7TLR8NUDT1
SCHEMBL20199817 0.91 TLR7 (1.00) TLR7TLR8NUDT1
SCHEMBL675585 0.90 TLR7 (0.85) TLR7TLR8NUDT1
SCHEMBL29663892 0.89 TLR7 (0.81) TLR7TLR8NUDT1
SCHEMBL22898736 0.89 TLR7 (0.81) TLR7TLR8NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230008368-A1 IMIDAZOQUINOLINE SUBSTITUTED PHOSPHORIC ESTER AGONIST, AND PREPARATION THEREFOR AND APPLICATION THEREOF SUZHOU ZELGEN BIOPHARMACEUTICALS CO., LTD. (CN) 2023-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230008368-A1 IMIDAZOQUINOLINE SUBSTITUTED PHOSPHORIC ESTER AGONIST, AND PREPARATION THEREFOR AND APPLICATION THEREOF TLR4, TLR7, TLR1 TLR7 2/4885TLR8 4/4885NUDT1 1225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.